Strengthening the Immune System
Nigella sativa (Black Seed) can increase the number of T cells either to increase natural killer cells. Effectiveness up to 72% when compared with placebo only 7%. Thus, taking Black Seed can boost the immune system. In 1993, DR. Basil Ali with his colleagues from the College of Medicine at the University of King Faisal Saud Pharmasetik publish in the journal. Black Seed extract capabilities are recognized Prof. G Reitmuller, Director of the Institute Immonologi from the University of Munich, can boost the immune system and can be used bioregulator. Thus, Black Seed can be used as a cure for diseases that attack the immune system, such as cancer and AIDS.
Improve memory, concentration, and alertness
With the content of linoleic acid (omega 6) and linoleic acid (omega 3), Black Seed is the nutrition for the brain cells to improve memory and intelligence. Black Seed also improve micro (blood circulation) to the brain and is very appropriate given the child’s age and growth of the elderly.
Increasing hormone bioactivity
Hormones are active substance which is produced by endocrine glands into the blood circulation. In the human body there are many different types of hormones on reproductive hormones ataranya associated with sexual arousal. Black Seed is one setrol content that serves as hormone synthesis and bioactivity.
Neutralize toxins in the body
Toxins may interfere with its metabolism and decrease the function of important organs like liver, lungs and brain. Symptoms of mild poisoning may include diarrhea, vomiting, dizziness, respiratory problems and reduce the power of concentration. Black Seed contains saponins that can neutralize and clean up toxins in the body.
Overcome sleep disorders and stress
Sapion contained in Black Seed has functions such as corticosteroids that can influence carbohydrate, protein and fat and also affects the functioning of the heart, kidneys, muscles and nerves. Sapion serves to defend itself from environmental changes, sleep disturbances and can relieve stress.
Anti-histamine.
Histamine is a substance released by bodily tissues, providing an allergic reaction such as bronchial asthma. Black Seed Oil is made from ‘can isolate dithimoquinone. This oil is often called volatile nigellone from nigella. Granting of this oil had a positive impact penderta bronchial asthma.
Research conducted by Nirmal Chakravaty MD in 1993 proved the crystals from negelone suppresive effect. These crystals can be inhibited protemkinasi C, a substance that triggers the release of histamine.
Other research also proves the same thing. This time it was done by Dr. Med. Peter Schleincher, immonologi experts from the University of Munich. Those who do test on 600 people who suffer from allergies. The results were quite convincing, 70% who suffer from dust allergies, pollen, acne and asthma recovered after being given a nigella oil (Black Seed). In practice Dr. Black Seed Schleincher prescribe ‘to patients suffering from influenza.
Improve the digestive tract and anti-bacterial
Black Seed oil contains the essential oil from a known volatif useful for improving digestion. Essential oil traditionally used to cure diarrhea. In 1992, Pakistan Journal of Pharmaceutical create a result that proves more potent volatile oils to kill strains of bacteria such as Cholera and E. Coli V compared with antibiotics such as tetracycline and ampicilin.
Breast milk launched
The combination of unsaturated fat and hormonoal structure contained in Black Seed oil ‘may launch breast milk. This research was later published in the research literature Potchetstroom University in 1989.
Supplementary nutrition to pregnant women and toddlers
In infancy, children need to improve isstem nutrusi naturally immune, especially during the rainy season is very easy to children with flu and colds. The content of Omega 3, Omega 6 and Omega 9 which are on the nutrients Habbatussauda’merupakan assist in the development of brain tissue.
Rejuvenate skin cells and delay the aging process
The skin is the outermost one of the important organs. Its function is to protect the body from a physical clash, bacteria and fungi. Black Seed is very good to maintain moisture, smoothness and youthfulness of skin.
Nutrition for the elderly and food supplement.
Rich in nutrients as additional energy is ideal for people who are elderly, especially to keep the immune system and brain cells revitalitas quickly so as not senile. Black Seed contains 15 kinds of compiler zest acid contents of protein, including the nine essential amino acids. Amino acids can not be produced by the body in sufficient quantity, and therefore must be obtained from food.
The principles of anti-tumor at the International Cancer Congress in New Delhi on last fall, Black Seed Oil ‘was introduced Immonobiologi cancer scientists from the Laboratory of South Carolina. Black Seed stimulates bone marrow and immune cells. Interferonnya produce normal cells against harmful viruses as well as destroy tumor cells and enhancing antibodies.
Nigella Sativa flowers
Sonntag, 27. Juni 2010
Dienstag, 9. März 2010
COREVITPLUS
COREVITPLUS contains the most powerful extracts, berries and specially Black Cumin seed oil, which is exhibited as one of the highest total antioxidant values among plant oils based on ORAC measurement.
Product Benefits and Contents:
Circulatory System
· Helps reduce the amount of bad cholesterol clogging the walls of arteries while increasing the level of good cholesterol in the system.
· Purifies the blood and improves circulation.
· Enhances the production of red and white blood cells.
· Strengthens the heart and alleviates heart palpitations.
· Helps reduce plaque build-up in the arteries.
· Maintains healthy blood pressure and blood sugar.
· Increases blood flow and fights off free radicals.
· Helps reduce the risk of heart disease.
Respiratory System
· Reduces the risk of having respiratory conditions like bronchitis, asthma and emphysema.
Digestive System
· Helps slow the digestive processes to feel full longer.
· Protects against digestive infections.
· Helps lower cholesterol levels.
· Helps improve appetite.
· Prevents liver failure.
· Disrupts the development of kidney stone formation.
· Reduces gum problem.
· Prevents mouth sore.
· Improves the health of the colon epithelial lining.
· Helps keep metabolic rate high, which in turn burns fat.
Integumentary System
· Protects the skin from ultraviolet damage and repairs skin damaged by the sun.
· Helps improve your complexion, remove dead skin and diminish wrinkles.
· Helps combat skin ulcers on the legs.
Nervous System
· Boosts enzymes that grow new nerve cells in the brain and protects the brain from oxidative stress and Alzheimer’s or dementia.
Visual System
· Strengthens the walls of blood vessels and improves blood flow through the small vessels that deal with the health of the eyes and can improve vision.
Immune System
· Helps the body fight viruses, allergens and carcinogens.
· Strengthens and maintains the immune system in and out and greatly reduces the possibility of developing any infection.
· Reduces stress.
· Boosts energy levels.
· Helps prevent cancer.
Endocrine System
· Protects the body from premature aging by increasing Vitamin C levels in the cells and scavenging for toxins so the organs can get rid of them.
· Helps slow the aging process in both body and brain.
· Helps in weight loss.
· Relieves insomnia and promotes restful sleep.
· Relieves back pain & muscle spasms.
· Helps protect the body tissue from oxygen-related damage.
Skeletal System
· Helps improve bone structure.
Reproductive System
· Slows growth of prostate cancer.
· Relieves fibrocystic diseases and painful menstruation.
· Improves sex life.
Black Cumin
A seed derived from a plant with botanical name Nigella sativa used as a nutritional supplement. It reduces the risk of having respiratory conditions like bronchitis, asthma and emphysema. It is widely used as a general tonic to boost immune system and helps prevent cancer.
Acai Berry
Known for its deep purple color, as well as for being a rich source of many important antioxidant vitamins. A fruit with high-ORAC value that helps slow the aging process in both body and brain.
Blackberry
An aggregate fruit that is composed of many smaller fruits called drupes. It contains ellagic acid, an antioxidant that has shown to protect the skin from ultraviolet damage and repairs skin damaged by the sun.
Blueberry
A berry full of nutrients and flavor, yet very low in calories. It boosts enzymes that grow new nerve cells in the brain and protects the brain from oxidative stress and Alzheimer’s or dementia.
Cranberry
A relatively small, red berry which grows on low-hanging vines in temperate zones. It contains flavonoids that help reduce the amount of bad cholesterol clogging the walls of arteries while increasing the level of good cholesterol in the system.
Raspberry
Composed of many seed-containing fruit sections called drupelets. It is packed with fiber that helps slow the digestive processes to feel full longer and manganese, a trace mineral that helps keep metabolic rate high, which in turn burns fat.
Strawberry
A delicious and nutrition-rich red colored berry. It is a rich source of many health promoting phyto-nutrients, minerals and vitamins that are essential for optimum health. It has potential health benefits against cancer, aging, inflammation and neurological diseases.
Bilberry Extract
Derived from the bilberry plant – containing edible berries. It strengthens the walls of blood vessels and improves blood flow through the small vessels that deal with the health of the eyes and can improve vision.
Grapeseed Extract
Contains a vast array of health-giving ingredients such as protein, lipids, carbohydrates and bioflavonoids. It helps the body fight viruses, allergens and carcinogens. It protects the body from premature aging by increasing Vitamin C levels in the cells and scavenging for toxins so the organs can get rid of them.
Green Tea Leaf Extract
Rich in antioxidant that protects against digestive and respiratory infections and helps lower cholesterol levels. It also helps reduce the risk of heart disease, cancer and prevents liver failure.
Mangosteen Fruit Extract
Strengthens the immune system in and out and greatly reduces the possibility of developing any infection. It helps improve appetite, bone structure, skin condition, purifies the blood and improves circulation in addition to strengthening the heart.
Noni Fruit Extract
An antioxidant and is rich in Vitamin C. It helps reduce asthma, flu and skin infection which is caused by bacteria. It also strengthens the heart and alleviates heart palpitations. It cleans the blood, builds the immune system and used as a treatment for bladder infections, diabetes, colds and constipation.
Pomegranate Fruit Extract
Contains a high level of antioxidants and contains many vitamins and minerals which helps reduce plaque build-up in the arteries. It lowers cholesterol, slows growth of prostate cancer, increases blood flow and fights off free radicals.
Wolfberry Fruit Extract
Also called red fruit or eye-clearing fruit. It maintains healthy immune system, improving eye conditions, supports healthy liver function and maintains healthy blood pressure and blood sugar.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Product Benefits and Contents:
Circulatory System
· Helps reduce the amount of bad cholesterol clogging the walls of arteries while increasing the level of good cholesterol in the system.
· Purifies the blood and improves circulation.
· Enhances the production of red and white blood cells.
· Strengthens the heart and alleviates heart palpitations.
· Helps reduce plaque build-up in the arteries.
· Maintains healthy blood pressure and blood sugar.
· Increases blood flow and fights off free radicals.
· Helps reduce the risk of heart disease.
Respiratory System
· Reduces the risk of having respiratory conditions like bronchitis, asthma and emphysema.
Digestive System
· Helps slow the digestive processes to feel full longer.
· Protects against digestive infections.
· Helps lower cholesterol levels.
· Helps improve appetite.
· Prevents liver failure.
· Disrupts the development of kidney stone formation.
· Reduces gum problem.
· Prevents mouth sore.
· Improves the health of the colon epithelial lining.
· Helps keep metabolic rate high, which in turn burns fat.
Integumentary System
· Protects the skin from ultraviolet damage and repairs skin damaged by the sun.
· Helps improve your complexion, remove dead skin and diminish wrinkles.
· Helps combat skin ulcers on the legs.
Nervous System
· Boosts enzymes that grow new nerve cells in the brain and protects the brain from oxidative stress and Alzheimer’s or dementia.
Visual System
· Strengthens the walls of blood vessels and improves blood flow through the small vessels that deal with the health of the eyes and can improve vision.
Immune System
· Helps the body fight viruses, allergens and carcinogens.
· Strengthens and maintains the immune system in and out and greatly reduces the possibility of developing any infection.
· Reduces stress.
· Boosts energy levels.
· Helps prevent cancer.
Endocrine System
· Protects the body from premature aging by increasing Vitamin C levels in the cells and scavenging for toxins so the organs can get rid of them.
· Helps slow the aging process in both body and brain.
· Helps in weight loss.
· Relieves insomnia and promotes restful sleep.
· Relieves back pain & muscle spasms.
· Helps protect the body tissue from oxygen-related damage.
Skeletal System
· Helps improve bone structure.
Reproductive System
· Slows growth of prostate cancer.
· Relieves fibrocystic diseases and painful menstruation.
· Improves sex life.
Black Cumin
A seed derived from a plant with botanical name Nigella sativa used as a nutritional supplement. It reduces the risk of having respiratory conditions like bronchitis, asthma and emphysema. It is widely used as a general tonic to boost immune system and helps prevent cancer.
Acai Berry
Known for its deep purple color, as well as for being a rich source of many important antioxidant vitamins. A fruit with high-ORAC value that helps slow the aging process in both body and brain.
Blackberry
An aggregate fruit that is composed of many smaller fruits called drupes. It contains ellagic acid, an antioxidant that has shown to protect the skin from ultraviolet damage and repairs skin damaged by the sun.
Blueberry
A berry full of nutrients and flavor, yet very low in calories. It boosts enzymes that grow new nerve cells in the brain and protects the brain from oxidative stress and Alzheimer’s or dementia.
Cranberry
A relatively small, red berry which grows on low-hanging vines in temperate zones. It contains flavonoids that help reduce the amount of bad cholesterol clogging the walls of arteries while increasing the level of good cholesterol in the system.
Raspberry
Composed of many seed-containing fruit sections called drupelets. It is packed with fiber that helps slow the digestive processes to feel full longer and manganese, a trace mineral that helps keep metabolic rate high, which in turn burns fat.
Strawberry
A delicious and nutrition-rich red colored berry. It is a rich source of many health promoting phyto-nutrients, minerals and vitamins that are essential for optimum health. It has potential health benefits against cancer, aging, inflammation and neurological diseases.
Bilberry Extract
Derived from the bilberry plant – containing edible berries. It strengthens the walls of blood vessels and improves blood flow through the small vessels that deal with the health of the eyes and can improve vision.
Grapeseed Extract
Contains a vast array of health-giving ingredients such as protein, lipids, carbohydrates and bioflavonoids. It helps the body fight viruses, allergens and carcinogens. It protects the body from premature aging by increasing Vitamin C levels in the cells and scavenging for toxins so the organs can get rid of them.
Green Tea Leaf Extract
Rich in antioxidant that protects against digestive and respiratory infections and helps lower cholesterol levels. It also helps reduce the risk of heart disease, cancer and prevents liver failure.
Mangosteen Fruit Extract
Strengthens the immune system in and out and greatly reduces the possibility of developing any infection. It helps improve appetite, bone structure, skin condition, purifies the blood and improves circulation in addition to strengthening the heart.
Noni Fruit Extract
An antioxidant and is rich in Vitamin C. It helps reduce asthma, flu and skin infection which is caused by bacteria. It also strengthens the heart and alleviates heart palpitations. It cleans the blood, builds the immune system and used as a treatment for bladder infections, diabetes, colds and constipation.
Pomegranate Fruit Extract
Contains a high level of antioxidants and contains many vitamins and minerals which helps reduce plaque build-up in the arteries. It lowers cholesterol, slows growth of prostate cancer, increases blood flow and fights off free radicals.
Wolfberry Fruit Extract
Also called red fruit or eye-clearing fruit. It maintains healthy immune system, improving eye conditions, supports healthy liver function and maintains healthy blood pressure and blood sugar.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Description
Nigella Seeds, or Black Cummin.
Agrostemma githagoNigella damascenaNigella sativaBy DR. F. A. FLÜCKIGER, Professor in the University of Bern.
These seeds, which had a place in the Bengal Pharmacopoeia (1844), are included in the Pharmacopoeia of India (1868) among the "non-officinal" articles. But, as they are still of considerable importance in the East, and are even in use in some parts of Europe, I have thought that a few particulars regarding the experiments I have made upon them may not be uninteresting to the readers of the Pharmaceutical Journal.
Name.—In pharmacy they have been termed Semen Nigellae, s. Melanthii, s. Cumini nigri. In English the plant bears the name of Nigella, Black Cummin, Gith, or Bishopswort; in German the seeds are called Schwarzkümmel or Nardensame; in French Cumin noir, Graine de Nigelle romaine, or Poivrette. Most of the Indian names signify, when translated, Black Cummin.
Botanical Origin.—Nigella sativa, L. (N. indica, Roxb.), belongs to the Order Ranunculaceae and is an annual herb, 8 to 12 inches high, with leaves cut into numerous, narrow, pinnate segments. The flowers are solitary, terminal, without an involucre; the petals blue and white, with greenish glands. The capsule is formed of 3 to 6 carpels, opening by the ventral suture. The plant grows on the Mediterranean coasts, in Egypt and Trans-Caucasia, whence it has spread to India. Boissier (Flora Orientalis, i, 68.) regards the var. β brackyloba, occurring in Cilicia and Syria, as the original type of the plant in a wild state.
Nigella sativa is now widely distributed as a corn-field weed throughout temperate Europe and America, (Though occasionally cultivated in gardens, the plant is scarcely naturalized in the United States.—EDITOR AMER. JOUR. PHARM.) though not in Britain. In Germany it is cultivated to some extent near Erfurt.
History.—Nigella is thought by some to be the kezach of Isaiah (xxviii, 25), translated in the English Bible fitches.
Dioscorides described the plant clearly under the name of Mελανθιον. Pliny called it Git, under which appellation it is found among the plants which Charlemagne ordered to be cultivated on the imperial farms of his dominions. This name, however, was frequently applied in the middle ages to the Corn Cockle, Agrostemma Githago, L., which is, indeed, termed by Gerarde Bastard Nigella. In his time, nigella was commonly sown in gardens, the seeds being used medicinally in wine as a spicy stimulant, and also as a perfume, for he says "it serveth well among other sweets to put into sweet waters, bagges, and odoriferous powders."
Nigella seeds had a place in the London Pharmacopoeia as late as the edition of 1721. In the East, the seeds have been extensively used from the remotest times to the present day.
Description.—The seeds are about 1/16th of an inch long, of an irregular, compressed pyramidal form, 3 or 4-sided, with an oblique rounded base, whence sharp ridges proceed towards the blunt summit of the seed. The surface is black, rough, granular, and devoid of polish. The seeds have an aromatic taste, and, when crushed, considerable fragrance. (* Those of the nearly allied N. Damascena, L., are rather more ovoid, less sharply ridged, less aromatic, and not pungent.)
Microscopical Structure.—The albumen consists of large polyhedral cells, and is covered by a thin brown tegmen. The testa presents two or three rows of more or less thick-walled cells, the inner being elongated in a direction parallel to the surface of the seed, the outer vaulted, and a certain number of them, chiefly those forming the ridges, prominently conical. The whole testa is blackish or dark bluish. The embryo is situated near the apex of the seed.
The tissue of the albumen abounds in fat oil and in granular albuminous matters; it is not altered by a salt of iron.
Chemical Composition.—Reinsch in 1841 obtained from this seed 35.8 per cent. of fat oil, 0.8 per cent of volatile oil, and only 0.6 per cent. of ash. He gave the name of Nigellin to a bitter extract resembling turpentine, yet soluble in water as well as in alcohol, though not in ether.
By submitting 25 lbs. of fresh seed to distillation, I obtained a nearly colorless essential oil in even smaller quantity than Reinsch. It has a slight odor, somewhat resembling that of parsley oil, with a magnificant bluish fluorescence, as already remarked by Reinsch.
In a column 50 mm. long, this oil deviates the ray of polarized light 9.8° to the left. Its specific gravity is 0.8909. The chief part of it, when distilled with chloride of calcium in a current of dry carbonic acid, comes over at 493° (256° C.) In an elementary analysis (Performed in my laboratory by Dr. Kraushaar.) it yielded: carbon 83.3, and hydrogen 11.8 per cent, corresponding to the formula, 2C10H16+H2O.
The residual portion was almost entirely devoid of deviating power; it yielded: carbon 87.89, and hydrogen 11.72 per cent., after having been rectified by means of sodium. This part of the oil consequently belongs to the formula C10H16.
I extracted the fat oil, by means of boiling ether, from seed grown in Germany, previously finely powdered. The oil thus obtained, which necessarily included some essential oil, imparting to the other its fluorescence, amounted to 25.6 per cent. It is a fluid fat, which does not congeal at + 5° (-15 °C.); it was found to consist chiefly of olein, besides which it yielded a considerable amount of a solid fatty acid, the crystals of which, after reiterated purification, melted at 131° (55° C.) The melting point did not rise by recrystallization, the acid being probably a mixture of palmitinic and myristic acids.
Nigella seeds, powdered and dried over sulphuric acid, yielded 3.3195 (On an average of three experiments made in my laboratory.) per cent. of nitrogen, answering to about 21 1/2 per cent. of albuminous matter.
Uses.—It is stated in the Pharmacopoeia of India, that nigella seeds are carminative, and they were formerly so regarded in Europe. In the East generally they are used as a condiment to food, and in Greece, Turkey and Egypt they are frequently strewed over the surface of bread and cakes in the same manner as anise or sesame. The fixed oil of the seeds is also expressed for use.
I have no recent statistics indicating the extent to which the seed is grown, but may state, on the authority of an official French document that, during the year 1854-55, 83 quarters, worth 2592 rupees, were exported from Madras to Ceylon.—Pharm. Journ., Lond., Aug. 26, 1871.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Agrostemma githagoNigella damascenaNigella sativaBy DR. F. A. FLÜCKIGER, Professor in the University of Bern.
These seeds, which had a place in the Bengal Pharmacopoeia (1844), are included in the Pharmacopoeia of India (1868) among the "non-officinal" articles. But, as they are still of considerable importance in the East, and are even in use in some parts of Europe, I have thought that a few particulars regarding the experiments I have made upon them may not be uninteresting to the readers of the Pharmaceutical Journal.
Name.—In pharmacy they have been termed Semen Nigellae, s. Melanthii, s. Cumini nigri. In English the plant bears the name of Nigella, Black Cummin, Gith, or Bishopswort; in German the seeds are called Schwarzkümmel or Nardensame; in French Cumin noir, Graine de Nigelle romaine, or Poivrette. Most of the Indian names signify, when translated, Black Cummin.
Botanical Origin.—Nigella sativa, L. (N. indica, Roxb.), belongs to the Order Ranunculaceae and is an annual herb, 8 to 12 inches high, with leaves cut into numerous, narrow, pinnate segments. The flowers are solitary, terminal, without an involucre; the petals blue and white, with greenish glands. The capsule is formed of 3 to 6 carpels, opening by the ventral suture. The plant grows on the Mediterranean coasts, in Egypt and Trans-Caucasia, whence it has spread to India. Boissier (Flora Orientalis, i, 68.) regards the var. β brackyloba, occurring in Cilicia and Syria, as the original type of the plant in a wild state.
Nigella sativa is now widely distributed as a corn-field weed throughout temperate Europe and America, (Though occasionally cultivated in gardens, the plant is scarcely naturalized in the United States.—EDITOR AMER. JOUR. PHARM.) though not in Britain. In Germany it is cultivated to some extent near Erfurt.
History.—Nigella is thought by some to be the kezach of Isaiah (xxviii, 25), translated in the English Bible fitches.
Dioscorides described the plant clearly under the name of Mελανθιον. Pliny called it Git, under which appellation it is found among the plants which Charlemagne ordered to be cultivated on the imperial farms of his dominions. This name, however, was frequently applied in the middle ages to the Corn Cockle, Agrostemma Githago, L., which is, indeed, termed by Gerarde Bastard Nigella. In his time, nigella was commonly sown in gardens, the seeds being used medicinally in wine as a spicy stimulant, and also as a perfume, for he says "it serveth well among other sweets to put into sweet waters, bagges, and odoriferous powders."
Nigella seeds had a place in the London Pharmacopoeia as late as the edition of 1721. In the East, the seeds have been extensively used from the remotest times to the present day.
Description.—The seeds are about 1/16th of an inch long, of an irregular, compressed pyramidal form, 3 or 4-sided, with an oblique rounded base, whence sharp ridges proceed towards the blunt summit of the seed. The surface is black, rough, granular, and devoid of polish. The seeds have an aromatic taste, and, when crushed, considerable fragrance. (* Those of the nearly allied N. Damascena, L., are rather more ovoid, less sharply ridged, less aromatic, and not pungent.)
Microscopical Structure.—The albumen consists of large polyhedral cells, and is covered by a thin brown tegmen. The testa presents two or three rows of more or less thick-walled cells, the inner being elongated in a direction parallel to the surface of the seed, the outer vaulted, and a certain number of them, chiefly those forming the ridges, prominently conical. The whole testa is blackish or dark bluish. The embryo is situated near the apex of the seed.
The tissue of the albumen abounds in fat oil and in granular albuminous matters; it is not altered by a salt of iron.
Chemical Composition.—Reinsch in 1841 obtained from this seed 35.8 per cent. of fat oil, 0.8 per cent of volatile oil, and only 0.6 per cent. of ash. He gave the name of Nigellin to a bitter extract resembling turpentine, yet soluble in water as well as in alcohol, though not in ether.
By submitting 25 lbs. of fresh seed to distillation, I obtained a nearly colorless essential oil in even smaller quantity than Reinsch. It has a slight odor, somewhat resembling that of parsley oil, with a magnificant bluish fluorescence, as already remarked by Reinsch.
In a column 50 mm. long, this oil deviates the ray of polarized light 9.8° to the left. Its specific gravity is 0.8909. The chief part of it, when distilled with chloride of calcium in a current of dry carbonic acid, comes over at 493° (256° C.) In an elementary analysis (Performed in my laboratory by Dr. Kraushaar.) it yielded: carbon 83.3, and hydrogen 11.8 per cent, corresponding to the formula, 2C10H16+H2O.
The residual portion was almost entirely devoid of deviating power; it yielded: carbon 87.89, and hydrogen 11.72 per cent., after having been rectified by means of sodium. This part of the oil consequently belongs to the formula C10H16.
I extracted the fat oil, by means of boiling ether, from seed grown in Germany, previously finely powdered. The oil thus obtained, which necessarily included some essential oil, imparting to the other its fluorescence, amounted to 25.6 per cent. It is a fluid fat, which does not congeal at + 5° (-15 °C.); it was found to consist chiefly of olein, besides which it yielded a considerable amount of a solid fatty acid, the crystals of which, after reiterated purification, melted at 131° (55° C.) The melting point did not rise by recrystallization, the acid being probably a mixture of palmitinic and myristic acids.
Nigella seeds, powdered and dried over sulphuric acid, yielded 3.3195 (On an average of three experiments made in my laboratory.) per cent. of nitrogen, answering to about 21 1/2 per cent. of albuminous matter.
Uses.—It is stated in the Pharmacopoeia of India, that nigella seeds are carminative, and they were formerly so regarded in Europe. In the East generally they are used as a condiment to food, and in Greece, Turkey and Egypt they are frequently strewed over the surface of bread and cakes in the same manner as anise or sesame. The fixed oil of the seeds is also expressed for use.
I have no recent statistics indicating the extent to which the seed is grown, but may state, on the authority of an official French document that, during the year 1854-55, 83 quarters, worth 2592 rupees, were exported from Madras to Ceylon.—Pharm. Journ., Lond., Aug. 26, 1871.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Black seed a cure all
It is important to note that black seed should be taken everyday of your life as is water or bread. Then when you get any disease it is easily cured. The normal daily routine should be one t. of oil mixed with juice or honey. If a person is sick then the dosage should be doubled.
A great many people go wrong by taking more nigella sativa as thinking it is needed. More is not better. What I take is oil once a day and the regular seeds ground mixed with honey once a day. It is absolutely delicious.
A woman had cancer and she did the above and added garlic mixed with honey also and was cured of cancer in 4 months. As I cannot give medical advice, I can only tell you what others have done.
Nigella Sativa is a prophetic cure sent from God with the revelation that it cures all disease except death. My general feeling is first you must believe in the cure and then thank God because he cured you.
There are many brands on the market stay away from anything stating it s caraway. At the top of the forum are some suggested sites.
Sara
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
A great many people go wrong by taking more nigella sativa as thinking it is needed. More is not better. What I take is oil once a day and the regular seeds ground mixed with honey once a day. It is absolutely delicious.
A woman had cancer and she did the above and added garlic mixed with honey also and was cured of cancer in 4 months. As I cannot give medical advice, I can only tell you what others have done.
Nigella Sativa is a prophetic cure sent from God with the revelation that it cures all disease except death. My general feeling is first you must believe in the cure and then thank God because he cured you.
There are many brands on the market stay away from anything stating it s caraway. At the top of the forum are some suggested sites.
Sara
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Thymoquinone a tumour breakthrough.
Thymoquinone, a potential therapeutic agent of Nigella sativa, binds to site I of human serum albumin
G. Lupidia, 1, A. Scireb, 1, E. Camaionic, K.H. Khalifea, G. De Sanctisa, F. Tanfanib and E. Damianib, ,
a Dipartimento di Biologia M.C.A., Università degli Studi di Camerino, Camerino, Italy
b Dipartimento di Biochimica, Biologia e Genetica, Università Politecnica delle Marche, Ancona, Italy
c Dipartimento di Chimica e Tecnologia del Farmaco, Università degli Studi di Perugia, Perugia, Italy
Available online 18 February 2010.
Abstract
Thymoquinone (TQ) is the main constituent of Nigella sativa essential oil which shows promising in vitro and in vivo antineoplastic growth inhibition against various tumour cell lines. Because of the increasing interest to test it in pre-clinical and clinical researches for assessing its health benefits, we here evaluate the interactions between TQ and human serum albumin (HSA), a possible carrier of this drug in vivo. Binding to HSA was studied using different spectroscopic techniques. Fourier transform infrared (FT-IR) and circular dichroism (CD) spectroscopies suggest that the association between TQ and HSA does not affect the secondary structure of HSA. Using fluorescence spectroscopy, one mole of TQ was found to bind one mole of HSA with a binding constant of 2.39 ± 0.2 104 M−1. At 25 °C (pH 7.4), van’t Hoff’s enthalpy and entropy that accompany the binding were found to be −10.24 kJ/mol−1 and 45 J/mol−1K−1 respectively. The thermodynamic analysis of the TQ-HSA complex formation shows that the binding process is enthalpy driven and spontaneous, and that hydrophobic interactions are the predominant intermolecular forces stabilizing the complex. Furthermore, displacement experiments using warfarin and ibuprofen indicate that TQ could bind to site I of HSA, which is also in agreement with the results of the molecular modeling study.
Keywords: Thymoquinone; Nigella sativa; Human serum albumin; Drug-protein complex; FT-IR; Fluorescence quenching; Circular dichroism; Molecular docking
Abbreviations: TQ, thymoquinone; DHTQ, dihydrothymoquinone; DHTQ-GS, glutathionyl-dihydrothymoquinone; HSA, Human serum albumin; CD, Circular Dichroism; FT-IR, Fourier transform infrared; GSH, glutathione; NADH, nicotinamide adenine dinucleotide reduced form; NADPH, nicotinamide adenine dinucleotide phosphate reduced form.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.taylor-jackson.com//
G. Lupidia, 1, A. Scireb, 1, E. Camaionic, K.H. Khalifea, G. De Sanctisa, F. Tanfanib and E. Damianib, ,
a Dipartimento di Biologia M.C.A., Università degli Studi di Camerino, Camerino, Italy
b Dipartimento di Biochimica, Biologia e Genetica, Università Politecnica delle Marche, Ancona, Italy
c Dipartimento di Chimica e Tecnologia del Farmaco, Università degli Studi di Perugia, Perugia, Italy
Available online 18 February 2010.
Abstract
Thymoquinone (TQ) is the main constituent of Nigella sativa essential oil which shows promising in vitro and in vivo antineoplastic growth inhibition against various tumour cell lines. Because of the increasing interest to test it in pre-clinical and clinical researches for assessing its health benefits, we here evaluate the interactions between TQ and human serum albumin (HSA), a possible carrier of this drug in vivo. Binding to HSA was studied using different spectroscopic techniques. Fourier transform infrared (FT-IR) and circular dichroism (CD) spectroscopies suggest that the association between TQ and HSA does not affect the secondary structure of HSA. Using fluorescence spectroscopy, one mole of TQ was found to bind one mole of HSA with a binding constant of 2.39 ± 0.2 104 M−1. At 25 °C (pH 7.4), van’t Hoff’s enthalpy and entropy that accompany the binding were found to be −10.24 kJ/mol−1 and 45 J/mol−1K−1 respectively. The thermodynamic analysis of the TQ-HSA complex formation shows that the binding process is enthalpy driven and spontaneous, and that hydrophobic interactions are the predominant intermolecular forces stabilizing the complex. Furthermore, displacement experiments using warfarin and ibuprofen indicate that TQ could bind to site I of HSA, which is also in agreement with the results of the molecular modeling study.
Keywords: Thymoquinone; Nigella sativa; Human serum albumin; Drug-protein complex; FT-IR; Fluorescence quenching; Circular dichroism; Molecular docking
Abbreviations: TQ, thymoquinone; DHTQ, dihydrothymoquinone; DHTQ-GS, glutathionyl-dihydrothymoquinone; HSA, Human serum albumin; CD, Circular Dichroism; FT-IR, Fourier transform infrared; GSH, glutathione; NADH, nicotinamide adenine dinucleotide reduced form; NADPH, nicotinamide adenine dinucleotide phosphate reduced form.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.taylor-jackson.com//
Dienstag, 23. Februar 2010
Alzheimer and cardiovascular Disease.
Head researcher, Prof. Dr. Maznah Ismail said the product is extracted from Nigella sativa seeds containing Thymoquinone (TQ) that has a very high anti-oxidant activity thus the capacity to maintain optimum health.
> Alzheimer > BioScience > Bird Communication > cardiovascular disease > Corporate Strategy > Disease > Thymoquinone > Thymoquinone Rich Fraction > TQRF > vascular disease“Cardiovascular diseases are the most common cause of death worldwide and have been associated with Alzheimer’s disease,” she said during a press conference organized by the University Research Management Centre and the Corporate Communication Division to introduce UPM New Products.
She said TQRF project was initiated since 2005 till 2008 and it works by regulating the cholesterol by a suppression that inhibits the synthesis of cholesterol.
“TQRF is extracted from Nigella Sativa seeds using an efficient and clean platform technology-Supercritical Fluid Extraction System (SFE)" said she, who is also assisted by co-researchers, Ghanya Al-Naqeeb and Norsharina Ismail from the Institure of Bioscience.
Prof. Dr. Maznah, who is also the Head of Molecular Biomedicine Laboratory, Institute of Bioscience, UPM said the reason of choosing Nigella Sativa seeds specially from Yemen, Iran and Sudan is because the TQ oil produced 40% more than the seeds from India and Sri Lanka.
She added that products currently available in the market prepared using technology are not capable of trapping TQ.
In addition, Deputy Vice Chancellor (Research and Innovation), Prof. Dato’ Dr. Abu Bakar Salleh said the product has great potentials to attract pharmaceutical companies.
“The technology is still at pre-commercialization stage and needs a clinical trial to human before it can be fully commercialized,” he added.
Patented in 2008, the product has received numerous accolades at the International Exhibition of Ideas Inventions New Products (iENA) 2009 in Nuremberg, German, two silver medals at the Malaysian Technology Expo (MTE) 2008 and 2009 and another three medals from UPM.
News by Section of Media, Publicity and Publication, Corporate Communication Division UPM (Noor Eszereen Juferi 03-89466013)
UPM Scientists Discovered Alzheimer and Cardiovascular Disease Prevention
next article 08.02.2010
A group of Universiti Putra Malaysia (UPM) researchers successfully created a product called, Thymoquinone Rich Fraction (TQRF) an agent to aid the treatment of Alzheimer and cardiovascular Disease.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
> Alzheimer > BioScience > Bird Communication > cardiovascular disease > Corporate Strategy > Disease > Thymoquinone > Thymoquinone Rich Fraction > TQRF > vascular disease“Cardiovascular diseases are the most common cause of death worldwide and have been associated with Alzheimer’s disease,” she said during a press conference organized by the University Research Management Centre and the Corporate Communication Division to introduce UPM New Products.
She said TQRF project was initiated since 2005 till 2008 and it works by regulating the cholesterol by a suppression that inhibits the synthesis of cholesterol.
“TQRF is extracted from Nigella Sativa seeds using an efficient and clean platform technology-Supercritical Fluid Extraction System (SFE)" said she, who is also assisted by co-researchers, Ghanya Al-Naqeeb and Norsharina Ismail from the Institure of Bioscience.
Prof. Dr. Maznah, who is also the Head of Molecular Biomedicine Laboratory, Institute of Bioscience, UPM said the reason of choosing Nigella Sativa seeds specially from Yemen, Iran and Sudan is because the TQ oil produced 40% more than the seeds from India and Sri Lanka.
She added that products currently available in the market prepared using technology are not capable of trapping TQ.
In addition, Deputy Vice Chancellor (Research and Innovation), Prof. Dato’ Dr. Abu Bakar Salleh said the product has great potentials to attract pharmaceutical companies.
“The technology is still at pre-commercialization stage and needs a clinical trial to human before it can be fully commercialized,” he added.
Patented in 2008, the product has received numerous accolades at the International Exhibition of Ideas Inventions New Products (iENA) 2009 in Nuremberg, German, two silver medals at the Malaysian Technology Expo (MTE) 2008 and 2009 and another three medals from UPM.
News by Section of Media, Publicity and Publication, Corporate Communication Division UPM (Noor Eszereen Juferi 03-89466013)
UPM Scientists Discovered Alzheimer and Cardiovascular Disease Prevention
next article 08.02.2010
A group of Universiti Putra Malaysia (UPM) researchers successfully created a product called, Thymoquinone Rich Fraction (TQRF) an agent to aid the treatment of Alzheimer and cardiovascular Disease.
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Diabetes research, Canada
Abstract
Antidiabetic Activity of Nigella sativa Seed Extract in Cultured Pancreatic β-cells, Skeletal Muscle Cells, and Adipocytes *
Authors: Ali Benhaddou-Andaloussi † ab; Louis C. Martineau † ab; Danielle Spoor ab; Tri Vuong ab; Charles Leduc a; Erik Joly bc; Andrew Burt d; Bouchra Meddah ae; Abdellatif Settaf e; John T. Arnason d; Marc Prentki bc; Pierre S. Haddad ab
Affiliations: a Department of Pharmacology, Universit de Montral, Montreal, and Nutraceuticals and Functional Foods Institute, Universit Laval, Quebec City, Quebec, Canada
b Montreal Diabetes Research Center, Montreal, Quebec, Canada
c Centre Hospitalier de l'Universit de Montral, Universit de Montral, Montreal, Quebec, Canada
d Department of Biology and Center for Research in Biopharmaceuticals and Biotechnology, University of Ottawa, Ottawa, Ontario, Canada
e Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco
Abstract
The seeds of Nigella sativa L. (NS), a plant of the Runanculaceae family, are used in traditional medicine in North Africa and the Middle East for the treatment of diabetes. Despite widespread use and a number of scientific studies, the target tissues and cellular mechanisms of action of this plant product are not well understood. This study evaluated the effects of NS seed crude ethanol extract on insulin secretion in INS832/13 and β TC-tet lines of pancreatic β-cells and on glucose disposal by C2C12 skeletal muscle cells and 3T3-L1 adipocytes. An 18-h treatment with NS amplified glucose-stimulated insulin secretion by more than 35% without affecting sensitivity to glucose. NS treatment also accelerated β-cell proliferation. An 18-h treatment with NS increased basal glucose uptake by 55% (equivalent to approximately two-fold the effect of 100 nM insulin) in muscle cells and approximately by 400% (equal to the effect of 100 nM insulin) in adipocytes; this effect was perfectly additive to that of insulin in adipocytes. Finally, NS treatment of pre-adipocytes undergoing differentiation accelerated triglyceride accumulation comparably with treatment with 10 μ M rosiglitazone. It is concluded that the well-documented in vivo antihyperglycemic effects of NS seed extract are attributable to a combination of therapeutically relevant insulinotropic and insulin-like properties.
*Dedicated to Professor John Thor Arnason of the University of Ottawa, Department of Biology, on the occasion of his sixtieth birthday.
Keywords: Glucose uptake; insulin secretion; natural health products; traditional medicine; type 2 diabetes mellitus
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
Antidiabetic Activity of Nigella sativa Seed Extract in Cultured Pancreatic β-cells, Skeletal Muscle Cells, and Adipocytes *
Authors: Ali Benhaddou-Andaloussi † ab; Louis C. Martineau † ab; Danielle Spoor ab; Tri Vuong ab; Charles Leduc a; Erik Joly bc; Andrew Burt d; Bouchra Meddah ae; Abdellatif Settaf e; John T. Arnason d; Marc Prentki bc; Pierre S. Haddad ab
Affiliations: a Department of Pharmacology, Universit de Montral, Montreal, and Nutraceuticals and Functional Foods Institute, Universit Laval, Quebec City, Quebec, Canada
b Montreal Diabetes Research Center, Montreal, Quebec, Canada
c Centre Hospitalier de l'Universit de Montral, Universit de Montral, Montreal, Quebec, Canada
d Department of Biology and Center for Research in Biopharmaceuticals and Biotechnology, University of Ottawa, Ottawa, Ontario, Canada
e Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco
Abstract
The seeds of Nigella sativa L. (NS), a plant of the Runanculaceae family, are used in traditional medicine in North Africa and the Middle East for the treatment of diabetes. Despite widespread use and a number of scientific studies, the target tissues and cellular mechanisms of action of this plant product are not well understood. This study evaluated the effects of NS seed crude ethanol extract on insulin secretion in INS832/13 and β TC-tet lines of pancreatic β-cells and on glucose disposal by C2C12 skeletal muscle cells and 3T3-L1 adipocytes. An 18-h treatment with NS amplified glucose-stimulated insulin secretion by more than 35% without affecting sensitivity to glucose. NS treatment also accelerated β-cell proliferation. An 18-h treatment with NS increased basal glucose uptake by 55% (equivalent to approximately two-fold the effect of 100 nM insulin) in muscle cells and approximately by 400% (equal to the effect of 100 nM insulin) in adipocytes; this effect was perfectly additive to that of insulin in adipocytes. Finally, NS treatment of pre-adipocytes undergoing differentiation accelerated triglyceride accumulation comparably with treatment with 10 μ M rosiglitazone. It is concluded that the well-documented in vivo antihyperglycemic effects of NS seed extract are attributable to a combination of therapeutically relevant insulinotropic and insulin-like properties.
*Dedicated to Professor John Thor Arnason of the University of Ottawa, Department of Biology, on the occasion of his sixtieth birthday.
Keywords: Glucose uptake; insulin secretion; natural health products; traditional medicine; type 2 diabetes mellitus
Where to buy Black seed oil
http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//
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