Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus.

Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A.

Source

Department of Physiology, College of Medicine, King Faisal University, Dammam, Saudi Arabia. aosbamosa@gmail.com

Abstract

Diabetes mellitus is a common chronic disease affecting millions of people world wide. Standard treatment is failing to achieve required correction of blood glucose in many patients. Therefore, there is a need for investigating potential hypoglycemic drugs or herbs to improve glycemic control in diabetic patients. Nigella sativa seeds were used as an adjuvant therapy in patients with diabetes mellitus type 2 added to their anti-diabetic medications. A total of 94 patient were recruited and divided randomly into three dose groups. Capsules containing Nigella sativa were administered orally in a dose of 1, 2 and 3 gm/day for three months. The effect of Nigella sativa on the glycemic control was assessed through measurement of fasting blood glucose (FBG), blood glucose level 2 hours postprandially (2 hPG), and glycosylated hemoglobin (HbA1c). Serum C-peptide and changes in body weight were also measured. Insulin resistance and beta-cell function were calculated usin the homeostatic model assessment (HOMA2). Nigella sativa at a dose of 2 gm/day caused significant reductions in FBG, 2hPG, and HbA1 without significant change in body weight. Fasting blood glucose was reduced by an average of 45, 62 and 56 mg/dl at 4, 8 and 12 weeks respectively. HbAlC was reduced by 1.52% at the end of the 12 weeks of treatment (P<0.0001). Insulin resistance calculated by HOMA2 was reduced significantly (P<0.01), while B-cell function was increased (P<0.02) at 12 weeks of treatment. The use of Nigella sativa in a dose of 1 gm/day also showed trends in improvement in all the measured parameters but it was not statistically significant from the baseline. However, no further increment in the beneficial response was observed with the 3 gm/day dose. The three doses of Nigella sativa used in the study did not adversely affect either renal functions or hepatic functions of the diabetic patients throughout the study period. In Conclusion: the results of this study indicate that a dose of 2 gm/ day of Nigella sativa might be a beneficial adjuvant to oral hypoglycemic agents in type 2 diabetic patients.

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Posted by haqqani-99 at 05:51 0 comments

Healing power of “HONEY” and the Black Seed “KLAUNJI”

Posted on June 20, 2011 by Aman News

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Healing power of “HONEY” and the Black Seed  “KLAUNJI”
The findings will amaze you and the research will delight you but you wont be shocked because you have known it all along! Truth revealed to muslims approximately 1400 years ago!
A powerful Verse from Quran that tells us where honey comes from, and is of different colors and is extremely beneficial for human health and can heal certain illnesses.
“…From with in their (the bees) abdomens comes a fluid of different colors; wherein is a healing for mankind …”
Surah an-Nahl-V 69.

Scientists after having done decades of research have agreed that Honey is safe and has no allergic or side effects. Fructose present in the honey encourages the blood absorb water without sodium from the intestine, a desirable effect that may save us from a lot of health problems. It reduces the duration of diarrhea in patients infected by salmonella, shigala and E. coli. This is due to the antibiotic and anti fungal properties of honey. Honey is an excellent healing agent and food substance containing rapidly absorbable sugars, proteins, minerals, vitamins and amino acids and healing agents. Did you know burns heal much faster with the topical application of honey??? And deep wounds like abdominal wounds disruptions after caesarian section also heal faster with the application of honey. One of these healing components known as ” Inhibine”, gets destroyed when heated. And we know that the Holy Prophet s.a.w. often liked to drink COLD water sweetened with honey. He s.a.w. is reported to have repeatedly advised a man suffering from gastro-intestinal problems to use honey to cure his ailment. The black seed (Nigella sativa), also known as the black caraway, the black cumin, or referred to in Arabic as Habbatul Barakah meaning the blessed seed, has also been used through out history ( in Arabian peninsula) to treat a variety of illnesses. In Urdu it is well known as:  KLAUNJI. Regarding the black seed, Abu Hurairah narrated that Allah’s Messenger Salalahu alayhe wa sallam, said, ” Use this black seed regularly, because it has cure for every disease except death.” (Bukhari) Flower of Black seed “ KLAUNJI ” Research on: Black seed is also finally getting some limelight from the world of medicine. The composition of black seed includes: 15 Amino acid, proteins, carbohydrates, oils ( both fixed and volatile), alkaloids, saponins, crude fiber and traces of minerals including :” calcium, potassium, iron, and sodium. There are still many components in black seeds that haven’t been identified!!!!!!!!!!!!! Besides its capacity to reduce inflammation, improve kidney functions, improve milk production in nursing mothers, strengthens the liver, and increase the body’s resistance against diseases, more recent benefits of the black seed includes its potential for the treatment of the bronchial asthma, bronchitis and other respiratory ailments, its capacity to lower excess blood pressure and improve the heart conditions and its antimicrobial activity against a host of a lot of disease causing organisms like E.coli and Staphylococcus etc. One of the most promising findings is the observations by the doctors that the black seed alone, or in combination with garlic is a potent anti-cancer agent! However,  KLAUNJI   “black seed”  or  “black seed oil”  should only be taken in small quantities as larger amounts can irritate the mucosal linings of the digestive tract. So these articles list only a sample of the research being carried out on these two amazing natural healers. It emphasizes the fact that “modern” science must come a full turn in the end and acknowledge the divine truth as revealed by Allah, Subhanatallah, and His Prophet Muhammad s.a.w- because science, once again, has finally discovered another miracle of the Quran. Allah subhanatala revealed this truth to muslims some 1400 years ago: ” And your Lord inspired to the bee, ‘Take for yourself among the mountains, houses (i.e. hives), and among the trees and [in] that which they construct. Then eat from all the fruit and follow the ways of your Lord laid down [for you].’ There emerges from there bellies a drink, varying in colors, in which there is healing for people. Indeed in that is a sign for people who give thought.” [16:68-69]

Honey is a good substitute for glucose, good for diarrhea, stomach and intestinal infections, ulcers, cough, skin, wounds, burns,  wea

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Posted by haqqani-99 at 05:51 0 comments

Research on: Black seed

Research on: Black seed is also finally getting some limelight from the world of medicine. The composition of black seed includes:
15 Amino acid, proteins, carbohydrates, oils ( both fixed and volatile), alkaloids, saponins, crude fiber and traces of minerals including :” calcium, potassium, iron, and sodium. There are still many components in black seeds that haven’t been identified!!!!!!!!!!!!!
Besides its capacity to reduce inflammation, improve kidney functions, improve milk production in nursing mothers, strengthens the liver, and increase the body’s resistance against diseases, more recent benefits of the black seed includes its potential for the treatment of the bronchial asthma, bronchitis and other respiratory ailments, its capacity to lower excess blood pressure and improve the heart conditions and its antimicrobial activity against a host of a lot of disease causing organisms like E.coli and Staphylococcus etc.
One of the most promising findings is the observations by the doctors that the black seed alone, or in combination with garlic is a potent anti-cancer agent!
However,  KLAUNJI   “black seed”  or  “black seed oil”  should only be taken in small quantities as larger amounts can irritate the mucosal linings of the digestive tract.
So these articles list only a sample of the research being carried out on these two amazing natural healers. It emphasizes the fact that “modern” science must come a full turn in the end and acknowledge the divine truth as revealed by Allah, Subhanatallah, and His Prophet Muhammad s.a.w- because science, once again, has finally discovered another miracle of the Quran. Allah subhanatala revealed this truth to muslims some 1400 years ago:
” And your Lord inspired to the bee, ‘Take for yourself among the mountains, houses (i.e. hives), and among the trees and [in] that which they construct. Then eat from all the fruit and follow the ways of your Lord laid down [for you].’ There emerges from there bellies a drink, varying in colors, in which there is healing for people. Indeed in that is a sign for people who give thought.”
[16:68-69]
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http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com

Black Seed Herbs

Black Seed Herbs

Overview

Around 1325 B.C., the Pharaoh Tutankhamen's servants entombed him with the precious artifacts he would require in the afterlife. Black seed was found among the selected items, proving that this spice's value extends back to ancient times. Roman, Greek and Arab cultures utilized it as an herbal remedy and a culinary ingredient. Today, medical researchers hypothesize that black seed may have antioxidant, anti-cancer and cardioprotective properties, according to professor of cancer research, Bharat Aggarwal, author of "Healing Spices."

Botanical Facts

Black seed comes from the Nigella sativa plant, which is native to the Mediterranean region, and now grows the Middle East and India as well. An annual herb, it blooms with fragile, pale blue flowers. It is often confused with several other black seed spices. Black seed, Nigella sativa, is commonly known as charnushka in the United States or kalonji in India. Black cumin, Buniun persicum, for example, is an altogether different spice, according to Aggarwal.

Physiological Action

One of black seed's primary bioactive components is thymolquinone, or TQ, which is found in its essential oil. So far, notes Aggarwal, botanists have established black seed as the only source of TQ. Scientific evidence shows that TQ can protect cells from oxidative damage. Additionally, TQ demonstrated anti-inflammatory action in the laboratory, according to Memorial Sloan-Kettering Cancer Center, MSKCC. Other constituents of black seed exhibited antihistamine, diuretic and antispasmodic properties. MSKCC also explains that black seed may be utilized for other conditions, such as asthma, epilepsy, liver protection and high blood pressure. Seek advice from a health practitioner before ...sing black seed medicinally.

Cancer

Among black seed's amazing properties is its ability to battle cancer, according to Aggarwal. According to a 2009 article in "Molecular Cancer Therapeutics," Aggarwal and other scientists found that TQ hindered tumor growth in laboratory animals. He also writes that this herb may be effective against ovarian, prostate, breast, colon and pancreatic cancers, to name a few. Moreover, black seed can initiate cancer cell death and halt the process of metastization, or the spreading of cancer cells. Ask your physician which herbal remedies are appropriate for you.

Using Black Seed

Black seed may be next to impossible to locate in your grocery store. Since it is a staple in Indian cuisine, however, you should be able to find it at an Indian marketplace or online. Kalonji, as it is known in India, is best dry roasted before using it to spice up chutneys, rice and curries. Black seed oil, or TQ, can be purchased in health food stores, and Aggarwal recommends daily consumption of TQ to derive its beneficial properties. Despite its many benefits, black seed is not an adequate replacement for advice and treatment from a qualified health care professional.

References

• "Molecular Cancer Therapeutics"; Thymoquinone Inhibits Tumor Angiogenesis and Tumor Growth Through Suppressing AKT and Extracellular Signal-regulated Kinase Signaling Pathways; July 2008
• "Healing Spices: How to Use 50 Everyday and Exotic Spices . . . "; Bharat Aggarwal; 2011
• Memorial Sloan-Kettering Cancer Center: Nigella Sativa

About this Author

Cindy Ell began writing professionally in 1990. A former medical librarian, she has written materials for hospitals, medical associations, the "Nashville Scene" and "Coping Magazine." She received her Bachelor of Arts in linguistics from the University of Massachusetts and her Master of Library and Information Science from Pratt Institute. She is currently a full-time freelance medical writer.

Read more: http://www.livestrong.com/article/477634-black-seed-herbs/#ixzz1QI7dBEzq

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asthma, black seed oil, insomnia, natural home remedies, Nigella seeds

Prophylactic effect of green tea and Nigella sativa extracts against fenitrothion-induced toxicity in rat parotid gland.

Source

Oral Biology Department, Faculty of Oral and Dental Medicine, Cairo University, 51 El Hadara st., Nerco, Degla, Cairo, Egypt.

Abstract

OBJECTIVE:

The aim of the present study was to compare between two antioxidant treatments in prevention of fenitrothion induced toxicity on rat parotid salivary gland.

DESIGN:

Forty adult male Wistar rats with an average weight of 120-150g were randomised into 4 groups, control (group I), fenitrothion administration (group II), fenitrothion administration 1h after green tea extract or Nigella sativa oil extract administration (groups III and IV respectively). The rats were then sacrificed after 28 days. The submandibular salivary glands were examined histologically, immunohistochemically and ultrastructurally.

RESULTS:

Histopathologically the fenitrothion group showed sign of acini degeneration represented by loss of normal architecture (amalgamation). The nuclei of the acinar cells revealed different sizes and shape (polymorphism). The acini relatively preserved their shape in both prophylactic groups (III and IV). Histomorphometric analysis showed significant increase in the optical density of caspase-3 cleaved activity in all experimental groups (p=0.0001). A significant difference was observed between both prophylactic experimental groups III and IV (p=0.0039). Ultrastructurally, the nuclei of serous acini in group II appeared pyknotic with segregation of chromatin. Condensation of the chromatin at the periphery of the nucleus was observed in the nuclei of group III, Clumping of the chromatin with darkly stained pyknotic nucleus was detected in group IV.

CONCLUSIONS:

In a rat model the administration of natural antioxidants could be of beneficial effect on prevention of cytotoxicity induced by organophosphorous compounds. However, green tea showed more promising results than that of Nigella sativa.

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asthma, black seed oil, insomnia, natural home remedies, Nigella seeds

Black Seed Oil takes you into the deeper more replenishing Delta Wave sleep

Black Seed Oil is a powerful antioxidant that can also help you overcome allergies and that has anti-fungal properties. For over 2000 years Black Seed Oil (Nigella Sativa and also known as Black Cumin) has been used in the Middle East and Far East but even today it is little known in the West.


How many people do you know long for a good nights sleep and to wake up in the morning fully rested. When your body achieves the rest it needs then it is in balance and can fight off disease and and give the healthy energising lifestyle that most people want.

Black Seed Oil takes you from the shallow Alpha Wave sleep into the deeper more replenishing Delta Wave sleep that allows you to wake refreshed and take on what the day has to offer with real joy. Black Seed Oil is not addictive and with absolutely no known side effects apart from the joy of waking refreshed. By taking just 1 teaspoonful (5ml) at night then the process of obtaining a blissful state of sleep can start to build.

Clients report that some of them find that it works immediately and for some it takes a couple of weeks to kick in.

However there are two or three cautions to think about so that you give this amazing oil the chance to do it’s work of relaxation.

Prepare for sleep and try to go to bed at around the same time every night by 11pm at the latest and do not eat heavily after 8pm. The old maxim of Breakfast like a King, Lunch like a Prince and dine like a Pauper is so true.

Furthermore avoid those sugary and milky bedtime drinks that we all know so well. Your Pancreas, which produces insulin to balance the sugar intake, needs to rest too and should not be springing into action a bedtime to deal with a large sugar rush.

Fairly quickly the user finds that they feel more rested, more relaxed and more capable of dealing with a new day’s activities. You have so much to gain by taking Black Seed Oil.

What price a good night’s sleep?

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