Nigella Sativa flowers

Freitag, 23. März 2012

The Blessed Seed for toothache

Toothache can be very painful and can occur from a variety of reasons.

If we care for our teeth, ie. daily cleaning them, these dilemma can still occur.

Black seed oil has been proven to be helpful in many cases simply by numbing the pain.

The anti inflammatory components in the blessed seed oil reduce swelling and its anti microbial components help to lessen the infection.

The blessed seed has been used for thousands of years for a natural home remedy for numerous ailments.

Only recently have we in the West been reintroduced to this ancient herbal remedy as we lost touch with herbs for healing with the modern pharmaceuticals that we are now accustomed to. The blessed seed's main advantage to modern drugs is that it has no known side affects. The vast majority of westerners that have tried it have been astounded how well they have responded to the health giving qualities of this remarkable herb.

Only some find that it is too pungent to taste, where they may take capsules that totally hide the taste.

In this time where we are inundated with more and more modern diseases the time is clear to look at a gift from nature that was clearly created for our optimum health.
Where to buy Black seed oil

Sonntag, 18. März 2012

Black Cumin Seed Extract

Gale Encyclopedia of Alternative Medicine
Paradise, Lee
700+ words
COPYRIGHT 2005 The Gale Group, Inc. (Hide copyright information) Copyright

Black cumin seed extract


Black cumin seed (Nigella sativa ) is an annual herbaceous plant and a member of the Ranunculaceae (buttercup) family. The fruit of the plant, the black seeds, accounts for its name. Black cumin seed (also called black seed) should not be confused with the herb, cumin (Cumunum cyminum, which is found in many grocery stores.

Considered native to the Mediterranean region, black cumin seed is cultivated in North Africa, Asia, and southeastern Europe. The largest producers of black cumin seed are Egypt, India, Pakistan, Iran, Iraq, and Turkey. Other species, such as Turkish black cumin (Nigella damascena ), are not used medicinally; and one type, Nigella garidella, is even poisonous.

Playfully referred to as "Love in the Mist," the black cumin seed plant has leaves that grow in pairs. The lower leaves are short and supported by slender stems, while the upper leaves generally grow to approximately 4 inches (10 cm) in length. The stalk of the plant, with its bluish white flower petals, can grow up to 18 inches (46 cm) in height while its fruit matures. At first, the seeds (the fruit of the plant) are held in a capsule in the center of the flower. The capsule opens upon maturity, revealing lightly colored seeds. It is only upon their exposure to air that the seeds become black.

Most often, the extract is produced by a process referred to as cold pressing. Temperatures no higher than 140–176°F (60–80°C) are applied to the seeds to help release the oil and preserve its benefits.

Rich with compounds such as nigellone and thymoquinone, black cumin seed is thought to contain over 100 ingredients; many remain unknown. However, experts agree that the most important compounds contained in the extract are the fatty acids and nutrients. Some components of black cumin seed extract are as follows:

myristic acid

palmitic acid

palmitoleic acid

stearic acid

oleic acid

linoleic acid (omega-6)

linolenic acid (omega-3)

arachidonic acid












General use

Black cumin seed has been used for centuries to treat respiratory and digestive problems, parasites, and inflammation. In ancient times, it was a remedy for a variety of health conditions including, colds, infections , headaches, and toothaches. The pharoahs' personal doctors are reported to have offered black cumin seed as a digestive aid after large meals. In fact, the extract was found in the tomb of King Tutankhamun, presumably to protect him in the afterlife.

Black cumin was also used as a remedy for skin diseases, dry skin, dandruff , and wounds .

At one time, black cumin seed was highly valued in Europe, but by the eighteenth century it had lost popularity, and was primarily used as a garden decoration. However, black cumin seed extract has regained popularity, and is now more widely used as a remedy in Europe and North America.

Many herbalists in current times embrace the healing properties of black cumin seed extract. For example, the extract is sometimes used externally to treat such skin care problems as psoriasis, eczema , and dry skin, and internally to treat stomach problems, respiratory ailments, and allergies , as well as to improve circulation and the immune system. In recent years, the extract has been the subject of immune system research.

One reason that is often given for the medicinal value of black cumin seed extract is its richness in polyunsaturated fatty acids, which help to produce prostaglandin E1. Prostaglandin E1 has many functions in the body, particularly in relation to the immune system, sugar metabolism, skin infections, and blood clots . It is also believed to protect the stomach lining.

Experts point out that the medicinal value may be provided by a unique and mysterious synergy (combined action) between the multitude of compounds present in the seeds. In addition, the extract, which is more concentrated than the seeds alone, is said to have greater healing power. A study at Cairo University in Eqypt showed a boost in antibacterial activity when the extract was used in combination with antibiotics such as streptomycin and gentamicin. In the same study, it showed additional antibacterial function in combination with erythromycin, tobramycin, doxycycline, and ampicillin, to kill E. Coli and the pathogenic yeast, Candida albicans. In addition, the study showed that the extract destroyed non-fatal subcutaneous staphylococcal infection in mice.

In 2003, one study noted the antifungal activity of black cumin seed extract against Candida albicans. In the study, mice were injected with Candida albicans, producing colonies of the organism in their liver, spleen, and kidneys. The researchers found that treatment with black cumin seed extract 24 hours after inoculation inhibited growth of the Candida albicans. With continued treatment, the extract significantly decreased the amount of Candida albicans found in the kidneys, liver, and spleen.

Aside from verifying its antibacterial and antifungal properties, researchers in recent years have tested the anti-inflammatory and analgesic effects of black cumin seed extract. In 1995, a group of scientists from the Department of Pharmacy at King's College in London found that the extract contains these properties, and is an antioxidant as well. They believe the anti-inflammatory and antioxidant abilities may be linked to ingredients such as thymoquinone and unsaturated fatty acids. Ultimately, the researchers concluded that black cumin seed extract is a justified treatment for rheumatism and related inflammatory diseases.

In 2001, a study performed at the Department of Pharmacology at King Faisal University in Saudi Arabia, reported anti-inflammatory and analgesic activity from the use of black cumin seed extract in animals. Paw edema (swelling) was reduced, as was reaction time in response to extreme heat. A 2003 study confirmed the analgesic effects of the extract. Studies in this area are likely to continue well into the future.

Researchers have also investigated and verified the extract's antihistamine activity, focusing on nigellone, an ingredient in black cumin seed extract. One 1993 study found that nigellone acted as an inhibitory agent on histamine (a substance involved in an allergic response, causing widening of blood vessels and tightening of bronchial passages) by inhibiting protein kinase C, known to initiate histamine release. In 2003, another study concluded that black seed oil is an effective treatment for allergies.


There are many applications made with black cumin seed extract. It can be found in teas, cough syrups, wound salves, compresses, massage oils, and other products. Black seed honey, soap, shampoo, and creams are all available commercially.

The extract has a strong flavor, which is improved by mixing it with honey. Herbal teas also help dilute its strength. As with any product used for medicinal purposes, it is important to read and follow the label instructions and warnings.

Although black cumin seed extract is not normally associated with severe skin irritation, a skin patch test should be conducted before using it for the first time. A small amount of diluted extract is placed on the inside of one elbow and covered with a bandage. After 24 hours, any redness or irritation is indicative of a negative reaction. This test should be done before a person proceeds with more extensive use.

Black cumin seed extract, in these dosages, is used as a remedy for the following conditions:

Headache. A few drops of the diluted extract are rubbed on the patient's forehead. Some patients may also find it helpful to take 1/2 teaspoon of the extract after breakfast, lunch, and dinner.

Cough. The dose is 1/2 teaspoon of diluted black cumin seed extract in the morning. A dry cough may require one teaspoon of the extract twice a day, mixed with one cup of coffee or hot tea. The extract can be rubbed on the chest and back for additional relief.

Common cold. One teaspoon of the extract is mixed with hot lemon tea and honey two or three times a day.

Diarrhea. One teaspoon of extract is mixed with one cup of yogurt twice a day.


Black cumin seed extract is not to be used during pregnancy .

Its safety in young children has not been established. Patients with liver or kidney disease are advised not to use this product unless a physician directs them to do so.

Black cumin seed extract is said to lower blood sugar levels; therefore, a diabetic patient is advised to consult with a physician before using.

Side effects

In general, if used as directed, black cumin seed extract is not associated with serious side effects. However, it has been reported that black cumin seed extract has a very low degree of toxicity, and may cause significant negative effects on liver and kidney function. A recommended daily allowance (RDA) has not been established for the extract, so it is wise to consult with a physician before beginning any internal treatment.


There does not appear to be a list of serious interactions associated with the use of black cumin seed extract; however, it is recommended that anyone taking prescription drugs seek the opinion of a physician and/or pharmacist before using black cumin seed extract in combination with the prescribed treatment.



Luetjohann, S. The Healng Power of Black Cumin. Twin Trees, WI: Lotus Light Publications, 1998.

Schleicher, P., and M. Saleh The Magical Egyptian Herb for Allergies, Asthma, and Immune Disorders. Rochester, VT: Healing Arts Press, 2000.


Albert-Matesz, R. "One of life's tiny treasures." The Herb Companion October 2003; 16: 16–25. 1998.

Ali, B. H., and G. Blunden. "Pharmacological and toxicological properties of Nigella sativa." Phytotherapy Research. (April 2003): 299–305.

Al-Ghamdi, M.S. "The anti-inflammatory, analgesic, and antipyretic activity of Nigella sativa." Journal of Ethnopharmacology. (June 2001): 45–48.

Al-Naggar, T. B., M. P. Gomez-Serranillos, M. E. Carretero, and A. M. Villar. "Neuropharmacological activity of Nigella sativa L Extracts." Journal of Ethnopharmacology. (September 2003): 63–68.

Chakravarty, N. "Inhibition of histamine release from mast cells by nigellone." Annals Allergy. (March 1993): 237–42.

Hanafy, M. S., and M. E. Hatem. "Studies on the antimicrobial activity of Nigella sativa seed (black cumin)." Journal of Ethnopharmacology. (September 1991): 275–8.

Kalus, U., A. Pruss, J. Bystron, A. Smekalova, J. J. Lichius, and H. Kiesewetter. "Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases." Phytotherapy Research. (December 2003): 1209–14.

Khan, M. A., M. K. Ashfaq, H. S. Zuberi, M. S. Mahmood, and A. H. Gilani. "The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds." Phytotherapy Research (February 2003): 183–6.

Where to buy Black seed oil

An alternative treatment for Candida infections with Nigella sativa extracts

A. Bita, A.F. Rosu, D. Calina, L. Rosu, O. Zlatian, C. Dindere, A. Simionescu

1University of Medicine and Pharmacy, Student, Craiova, Romania

2University of Medicine and Pharmacy, Clinical pharmacy, Craiova, Romania

3University of Medicine and Pharmacy, Microbiology, Craiova, Romania

4University of Craiova, Electric technology, Craiova, Romania


Background Nigella sativa is a herb from the Mediterranean region with antidiabetic, bronchodilator, antioxidant, hepatoprotective, lipid lowering, anti-inflammatory and analgesic properties.

Purpose This study aimed to reveal the antifungal activity of aqueous, methanolic and chloroform extracts obtained from the plant seeds, compared with the effect of traditional antifungals.

Materials and methods Using standard mycological diagnostic methodology The authors isolated and identified 20 strains of Candida albicans from pathological products collected from patients hospitalised in different departments of the Craiova Emergency Hospital. Aqueous, methanolic and chloroform extracts were made from the seeds of Nigella sativa, in decreasing dilutions, in which Wattman filter paper discs were soaked and dried and then used to achieve the antifungal graph by using the Kirby-Bauer diffusion technique. Simultaneously, the testing was repeated using standard antifungal disks (Becton Dickinson) and the two sets of results compared. The antifungal effect was assessed by measuring the diameter of the inhibition zone, noting the concentration per disk.

Results The results show that methanolic extracts of Nigella sativa have the strongest antifungal effect followed by the chloroform extracts. Aqueous extracts showed no antifungal activity.

Conclusions The research shows treatment with natural products in a good light as an alternative for treating fungal infections. The authors envisage Nigella sativa extract enhancing the effect of conventional therapy.

Where to buy Black seed oil

Mittwoch, 7. März 2012

Effect of Nigella sativa and bee honey on asthma

Nahid Mahmoud AL Ameen1*, Faisal Altubaigy2, Tamanna Jahangir3, Idriss Abdalla Mahday4, Esmaeel Abdurrahman Mohammed5 and Omer Abdel Aziz Musa6
1Department of Basic Science, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
2College of Dentistry Jazan University, Jazan, Saudi Arabia.
3Department of Toxicology, College of Pharmacy, Jazan University Jazan, Saudi Arabia.
4National Ribatt University Teaching Hospital Clinical Chemistry Lab, Khartoum Sudan.
5Department of Pathology, Faculty of Medicine Ribatt, University Khartoum, Sudan.
6Department of Physiology, Faculty of Medicine, Ribatt University, Khartoum, Sudan.
*Corresponding author. E-mail: Tel: 00966549299713.
Abbreviations: BH, Bee honey; FVC, forced vital capacity; PEFR, peak expiratory flow rate; TQ, thymoquinone; ROS, reactive oxygen species; NF-kB, nuclear factor-kappaB; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; FEV1, forced expiratory volume 1.
Accepted 8 November, 2011
Nigella sativa seeds and Bee honey (BH) had been widely used in traditional medicine. In the present study we assessed their effect in treating asthma. A dose of 2 g of whole N. sativa seeds and 1 teaspoon full of BH per day were taken by the subjects -5 asthmatics and 22 non-asthmatics, 8 to 40 years in Khartoum for three month. They were also asked to smell crushed seeds that were warped in porous cloth three times a day. We assessed the effects of both on pulmonary, renal and hepatic function. Regarding pulmonary function, there was a significant increase in forced vital capacity (FVC) (P=0.023) in asthmatics' group and peak expiratory flow rate (PEFR) (P = was 0.049) in non-asthmatics' group. For evaluating the toxicity of both renal and hepatic functions, both were assessed before and after treatment. Hepatic enzymes were spared whereas serum creatinine in non-asthmatics and blood urea in asthmatics and in those having upper limit blood urea decreased significantly (creatinine (P=0.049) and urea (P value = 0.023, 0.017, respectively). In conclusion both N. sativa and BH seem to have some benefits to asthmatics with no hepato-renal toxicity.
Where to buy Black seed oil

Montag, 5. März 2012

Control of disease including cancer with Food

Friday, February 24th, 2012

The concept of control of disease with food was first introduced to me decades ago by my close friend Barbara Kim Thigpen.

This is the research interest of her life and she is a very knowledgeable self taught individual. She knows more about nutrition as medicine than anyone I know. She should write some books on it to condense her research for the rest of us. Someday perhaps. While I was researching for a treatment for a recent patient to the Camelot clinic I ran into new research papers published on the NIH website called PubMed that sparked my interest. These papers were the result of a search on PubMed for nigella sativa cancer also called Black Cumin. It is an African spice well known in Egypt during the time of the pharaohs, King Tut was buried with a jar of the oil so it was highly regarded. Hipocrates said of it that it would cure almost anything except for death. My friend Kim would talk about it endlessly extolling its benefits and virtues. I was focused on alternative energy and electric propulsion at that time so it went in one ear and out the other.

Now years later while I am Chief of R&D for Camelot Cancer Care it suddenly becomes important to me and I am struck by how much of the information about this remarkable healing food substance I had retained from years of listening to Kim talk about this wonderful substance endlessly. It is funny. Men are not being rude when they kind of tune out the most important women in their lives. If you give them the information and they seem to shut down or ignore you ladies keep trying because while we might be focused on other things if we care about the person saying it then we are listening but just can not be overwhelmed at the time with other information when we are trying to accomplish other things requiring another intelligence skill set then the one you are accessing.

That said we move on to the second wonderful product that heals us from cancer. Turmeric. Curcumin is the active ingredient in Turmeric. This gives the Turmeric spice its yellow color. It is a rather dye like substance but cancer and a lot of other diseases just can’t stand it. PubMed search for Curcumin Cancer

I was researching for a treatment for a Liposarcoma patient and found that in a search for Curcumin Cancer Liposarcoma lt revealed this recent published article that showed a great deal of efficacy for curcumin in the treatment of this hard to treat liposarcoma. It immediately reminded me of Kim and her years long discussion with me about Curcumin at a time when I was researching something else and did not pay her much mind. (She is linked into this article as you might have guessed by now)

I then created a topical protocol based on this research data and our own in house clinical data for our patient and gave the patient a suggested protocol for the oral administration of this wonderful but ancient miracle food for use in conjunction with this new topical treatment. Since there is no noted cure for this disease if this treatment helps it will validate this early research finding. The publish date is only Jan 31 so it is likely that this is the first treatment for humans yet devised for this malignancy based on this recently published research.

When the treatment includes a diet change and some topical cream then why wait for some human trials. I gave it straight to the first patient I know with the ailment. If it helps or not I will report back here minus any personal data on the patient of course.

Kim mentioned many more natural food substances that would heal but I will wait for my follow on interview with her or some future book she publishes to discuss those.

Where to buy Black seed oil

Black seed is an effective antiinflammatory and analgesic substance


Animal studies have confirmed the popular claim that black seed is an effective antiinflammatory and analgesic substance. The mechanism by which black seed exerts its antiinflammatory action appears to be as a potent inhibitor of eicosanoid generation, namely thromboxane B 2 and leucotrienes B 4, by inhibiting both cyclooxygenase and lipooxygenase, respectively. In other studies, thymoquinone has been reported to have potent superoxide anion scavenging abilities and to inhibit iron-dependent microsomal lipid peroxidation. This is promising considering the fact that superoxide reacts with protein and non-protein sulfhydryls and polyunsaturated fats and initiates sprecific reactions, thus damaging cells and causing inflammation. Meanwhile free radical oxidative stress is implicated in many inflammatory diseases. Therefore, it is reasonable that the anti-inflammatory activities of thymoquinone are attributed to its antioxidant effects. Interestingly, it was found that the whole oil had both antioxidant and anti-eicosanoid effects greater than thymoquinone, the oil’s active constituent.

A recent study found black seed and thymoquinone may be an effective treatment for rheumatoid arthritis. This comes as no surprise, since it has been shown that thymoquinone is an inhibitor that is more potent than indomethacin of COX-2-catalyzed PGE2 production.

The immuno-modulatory properties of black seed and thymoquinone support its traditional use as a treatment for rheumatism and related inflammatory disorders.


Abdel-Fattah AM, Matsumoto K, Watanabe H. Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice. Eur J Pharmacol. 2000 Jul 14;400(1):89-97.

Al-Ghamdi MS. The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa. J Ethnopharmacol. 2001 Jun;76(1):45-8.

Badary OA, Taha RA, Gamal el-Din AM, et al. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol. 2003 May;26(2):87-98.

Gali-Muhtasib H, Roessner A, Schneider-Stock R. Thymoquinone: a promising anti-cancer drug from natural sources. Int J Biochem Cell Biol. 2006;38(8):1249-53.

Ghannadi A, Hajhashemi V, Jafarabadi H. An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. J Med Food. 2005 Winter;8(4):488-93.

Hajhashemi V, Ghannadi A, Jafarabadi H. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytother Res. 2004 Mar;18(3):195-9.

Houghton PJ, Zarka R, de las Heras B, et al. Fixed

Where to buy Black seed oil

Samstag, 3. März 2012

Preventative care at Brooksville Cardiology


Hernando Today

Published: March 01, 2012

Chronic diseases are the leading causes of death and disability in the United States, advises the Centers for Disease Control and Prevention (CDC).

Chronic diseases are heart disease, stroke, cancer, diabetes, and arthritis and are the most common and costly of all health problems for Americans.

These chronic diseases are also the most preventable, stressing the importance for early detection.

Some believe early detection, like an ounce of prevention, is worth a pound of cure.

One Hernando county physician has implemented a practical approach for local patients to spot small problems before they become big ones.

Dr. Adel M. Eldin, M.D., specializing in internal medicine and cardiology, his practice is Brooksville Cardiology, explained his health and wellness program, which focuses on preventative care. He presented his program to more than 50 participants gathered at Palace Grand in Spring Hill, listening to testimonials from patients who have experienced success with the cardiology center.

"It's possible to detect problems before there's an emergency and 95 percent preventable, given our knowledge, medications and lifestyle modifications," Eldin said.

But there's one problem, Medicare and other insurance companies don't cover preventive screenings without the presence of symptoms, he advised.

"Insurance focuses on illness, rather than wellness," he said. "Wellness is there for you."

"When you invest in your health, you won't have to be part of the insurance jungle out there." Eldin said. "I've spent five years introducing a new program that identifies risks, teaches preventive care and provides an on going partnership in healthy living."

Brooksville Cardiology is a medically supervised program to prevent disease and guide people into health-related choices. They review family and medical history, assess current status, identify areas that need attention and implement a plan. The patient is involved in the decisions for well being. His staff is trained to perform screenings, non-invasively to look inside arteries for plaque buildup that can cause strokes (brain shock), aneursyms and heart attacks.

One patient drives from Ocala to come to Brooksville Cardiology.

"Dr. Eldin showed me more compassion than any doctor my whole life," said Errol Wiles. "I signed up for this program two months ago. It's been a positive experience."

He mentioned that he plans to move to Jacksonville, but will continue being a patient, driving to Brooksville for appointments.

"We become your partner and coach, not just a specialist attending to one symptom at a time," said Dr. Eldin. "We have a model we are proud of."

The member fee is $150 per month. Covered medical services include two office visits for routine check-ups, baseline cardio-vascular testing including treadmill exercise stress test, echocardiogram, vascular studies, 24-hour Holter monitor testing, monthly Coumadin check, interrogation of cardiac devices, annual flu shot, year round supply of recommended supplement of Black seed, e-newsletter, personal access to physician through email up to one time per week and referrals to other specialists when needed. Members also receive access to a webinar which features educational programs on health.

There are no denials for coverage under the plan for pre-existing conditions and no additional payments are needed for tests such as co-pays. Additionally, there are no referrals or pre-authorizations for testing. Open enrollment is available throughout the year.

"This is the way health-care is headed," he said. "We want to boost the immune system and prevent diseases."

One supplement he recommends is Black seed, or Nigella sativa. It's also referred to as black cumin.

"Nigella sativa (black seed) is an important medicinal herb. In many Arabian, Asian and African countries, black seed oil is used as a natural remedy for a wide range of diseases, including various allergies," according to a study found on the U.S. National Library of Medicine and National Institutes for Health website.

Black seed oil proved to be an effective adjuvant for the treatment of allergic diseases, based on the research.

The seeds/oil has anti-inflammatory, analgesic, antipyretic, antimicrobial and antineoplastic activity. The oil decreases blood pressure and increases respiration, according to other research regarding its pharmacological and toxicological properties.

The seeds have been used in the Middle East to treat asthma, bronchitis, rheumatism and related inflammatory diseases.

Researchers at Kimmel Cancer Center, Thomas Jefferson University in Philadelphia have studied that thymoquinone, an extract of N. sativa seed oil, blocked pancreatic cancer cell growth and killed the cells, acting as a Histone deacetylase inhibitors (HDAC) for use in psychiatry and neurology as mood stabilizers and anti-epileptics

Studies are in the early stages.

"Black seed has been around for thousands of years," said Dr. Eldin. "It is an old remedy mentioned in the Bible and was found in King Tut's tomb."

Black seed is not recommended for patients undergoing treatments for a medical condition or if they are pregnant or lactating, according to information provided by Envirotech International, Inc., the manufacturer. More information can be found at

Nigella Sativa has five FDA patents in the United States and one in the United Kingdom for the treatment of diabetes, inhibition of cancer cell growth, improvement of the immune system, viral infections, psoriasis and asthma.

For more information, Brooksville Cardiology is located at 12082 Cortez Boulevard in Brooksville, call (352) 592-4938, or email A second office is located at 2204 Ashley Oaks Circle, Suite 102 in Wesley Chapel, call (813) 994-7790.

Brooksville Cardiology will have a Heart Health and Awareness Day at 5 p.m. on Mar. 15 at the Brooksville location, which is open to the community. For more information on events and the wellness program, Brooksville Cardiology is on Facebook.

Roxanne DeAngelis is a correspondent for Hernando Today. She can be reached at

Where to buy Black seed oil