Nigella Sativa flowers

Dienstag, 23. Februar 2010

Alzheimer and cardiovascular Disease.

Head researcher, Prof. Dr. Maznah Ismail said the product is extracted from Nigella sativa seeds containing Thymoquinone (TQ) that has a very high anti-oxidant activity thus the capacity to maintain optimum health.
> Alzheimer > BioScience > Bird Communication > cardiovascular disease > Corporate Strategy > Disease > Thymoquinone > Thymoquinone Rich Fraction > TQRF > vascular disease“Cardiovascular diseases are the most common cause of death worldwide and have been associated with Alzheimer’s disease,” she said during a press conference organized by the University Research Management Centre and the Corporate Communication Division to introduce UPM New Products.
She said TQRF project was initiated since 2005 till 2008 and it works by regulating the cholesterol by a suppression that inhibits the synthesis of cholesterol.

“TQRF is extracted from Nigella Sativa seeds using an efficient and clean platform technology-Supercritical Fluid Extraction System (SFE)" said she, who is also assisted by co-researchers, Ghanya Al-Naqeeb and Norsharina Ismail from the Institure of Bioscience.

Prof. Dr. Maznah, who is also the Head of Molecular Biomedicine Laboratory, Institute of Bioscience, UPM said the reason of choosing Nigella Sativa seeds specially from Yemen, Iran and Sudan is because the TQ oil produced 40% more than the seeds from India and Sri Lanka.

She added that products currently available in the market prepared using technology are not capable of trapping TQ.

In addition, Deputy Vice Chancellor (Research and Innovation), Prof. Dato’ Dr. Abu Bakar Salleh said the product has great potentials to attract pharmaceutical companies.

“The technology is still at pre-commercialization stage and needs a clinical trial to human before it can be fully commercialized,” he added.

Patented in 2008, the product has received numerous accolades at the International Exhibition of Ideas Inventions New Products (iENA) 2009 in Nuremberg, German, two silver medals at the Malaysian Technology Expo (MTE) 2008 and 2009 and another three medals from UPM.

News by Section of Media, Publicity and Publication, Corporate Communication Division UPM (Noor Eszereen Juferi 03-89466013)

UPM Scientists Discovered Alzheimer and Cardiovascular Disease Prevention

next article 08.02.2010

A group of Universiti Putra Malaysia (UPM) researchers successfully created a product called, Thymoquinone Rich Fraction (TQRF) an agent to aid the treatment of Alzheimer and cardiovascular Disease.
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Diabetes research, Canada

Antidiabetic Activity of Nigella sativa Seed Extract in Cultured Pancreatic β-cells, Skeletal Muscle Cells, and Adipocytes *

Authors: Ali Benhaddou-Andaloussi † ab; Louis C. Martineau † ab; Danielle Spoor ab; Tri Vuong ab; Charles Leduc a; Erik Joly bc; Andrew Burt d; Bouchra Meddah ae; Abdellatif Settaf e; John T. Arnason d; Marc Prentki bc; Pierre S. Haddad ab

Affiliations: a Department of Pharmacology, Universit de Montral, Montreal, and Nutraceuticals and Functional Foods Institute, Universit Laval, Quebec City, Quebec, Canada

b Montreal Diabetes Research Center, Montreal, Quebec, Canada

c Centre Hospitalier de l'Universit de Montral, Universit de Montral, Montreal, Quebec, Canada

d Department of Biology and Center for Research in Biopharmaceuticals and Biotechnology, University of Ottawa, Ottawa, Ontario, Canada

e Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohamed V University, Rabat, Morocco


The seeds of Nigella sativa L. (NS), a plant of the Runanculaceae family, are used in traditional medicine in North Africa and the Middle East for the treatment of diabetes. Despite widespread use and a number of scientific studies, the target tissues and cellular mechanisms of action of this plant product are not well understood. This study evaluated the effects of NS seed crude ethanol extract on insulin secretion in INS832/13 and β TC-tet lines of pancreatic β-cells and on glucose disposal by C2C12 skeletal muscle cells and 3T3-L1 adipocytes. An 18-h treatment with NS amplified glucose-stimulated insulin secretion by more than 35% without affecting sensitivity to glucose. NS treatment also accelerated β-cell proliferation. An 18-h treatment with NS increased basal glucose uptake by 55% (equivalent to approximately two-fold the effect of 100 nM insulin) in muscle cells and approximately by 400% (equal to the effect of 100 nM insulin) in adipocytes; this effect was perfectly additive to that of insulin in adipocytes. Finally, NS treatment of pre-adipocytes undergoing differentiation accelerated triglyceride accumulation comparably with treatment with 10 μ M rosiglitazone. It is concluded that the well-documented in vivo antihyperglycemic effects of NS seed extract are attributable to a combination of therapeutically relevant insulinotropic and insulin-like properties.

*Dedicated to Professor John Thor Arnason of the University of Ottawa, Department of Biology, on the occasion of his sixtieth birthday.

Keywords: Glucose uptake; insulin secretion; natural health products; traditional medicine; type 2 diabetes mellitus

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Acne Treatment

A Home Remedy for Acne – Nigella 22/02/10 Posted By: Acne Treatment Contributor

The nigella sativa, also known as the fennel flower, is a plant that has been cultivated for thousands of years and is used for medicinal purposes as a home remedy for acne and also as a spice. The plant is native of southwest Asia. For many years western civilisations have been unaware of its significance but it is now beginning to gain some recognition.

How Does Nigella Make a Good Home Remedy For Acne?

Nigella possesses an enermous number of properties and more than 200 types of complex chemical compounds such as alanine, cystine, glycine, linolenic-acid and potassium. It also has many properties that make it an effective home remedy for acne – it is antimicrobial, anti-inflammatorym analgesic, antipyretics and antineoplastic.

Nigella can also strengthen the immune system which is another way in which it is useful as a home remedy for acne. When the immune system is weak, the oil producing sebaceous glands and hair follicles within the skin are stimulated and become inflamed which causes an excess of sebum to be produced. Excessive sebum clogs the hair follicles which causes the acne breakout.

How to use Nigella as a Home Remedy For Acne

It is possible to buy nigella seeds in their natural form from an organic store and you can use these in cooking but you may need to get a little creative with your recipes as it is not really an everyday ingredient in western diets!

Perhaps a better way to use nigella as a home remedy for acne is to buy a good quality Nigella Sativa Oil as this contains all of the active ingredients of the seeds. Some brands of this oil also have other ingredients that are beneficial to your health such as omega 6 and omega 3.

Stir one teaspoon of the nigella oil into a bowl of very hot water and then hold your head over the bowl with a towel covering your head and the bowl. This will cause steam to rise which opens up the pores of the skin. The oil vaporizes and impregnates the skin through the open pores. Continue with this facial steam for around 15 minutes or as long as the steam continues to rise and then wash the face with cool water.

Where to buy Black seed oil

Sonntag, 21. Februar 2010

Cure All

The Oil That Can Change Your Life!

It is very rare that something comes along that can, by itself, change our lives. However, we would like to introduce you to a very special supplement - a pure, virgin, cold-pressed oil that can have a startling impact not just for your skin, but for virtually every aspect of your health.

Nigella Sativa Oil is possibly the most potent of all dietary supplements known to scientists. It contains over 100 known therapeutic compounds - a host of powerful agents that boost the body's immune system and impact our health in a way that no other supplement can.

The action of Nigella Sativa Oil has to be seen to be believed. Although it has been tradionally used for centuries in Asia to treat so many health problems, it is only in the last few decades that scientists have begun to take notice and investigate the incredible claims in controlled, clinical studies.

There are now over 200 independent published research papers confirming that Nigella Sativa Oil is really the closest thing known to a cure-all. The oil has been shown to exhibit the following qualities:

Analgesic: Relieves or dampens sensation of pain.

Anthelmintic: (Also know as vermicide or vermifuge.) Destroys and expels intestinal worms.

Anti-bacterial: Destroys or inhibits the growth of destructive bacteria.

Anti-Inflammatory: Reduces inflammation.

Anti-Microbial: Destroys or inhibits the growth of destructive microorganisms.

Antioxidant: Prevents or delays the damaging oxidisation of the body's cells - particularly useful against free radicals.

Anti-Pyretic: (Also known as ferbrifuge.) Exhibits a 'cooling action', useful in fever reduction.

Anti-spasmodic: Prevents or eases muscle spasms and cramps.

Anti-tumour: Counteracts or prevents the formation of malignant tumours

Carminative: Stimulates digestion and induces the expulsion of gas from the stomach and the intestines.

Diaphoretic: Induces perspiration during fever to cool and stimulate the release of toxins.

Diuretic: Stimulates urination to relieve bloating and rid the body of any excess water.

Digestive: Stimulates bile and aids in the digestive process.

Emmenagogue: Stimulates menstrual flow and activity.

Galactogogue: Stimulates the action of milk in new mothers.

Hypotensive: Reduces excess blood pressure.

Immunomodulator: Suppresses or strengthens immune system activity as needed for optimum balance.

Laxative: Causes looseness or relaxation of the bowels.

For more information on Nigella Sativa and details of published research, please see Nigella Sativa Research

Just look at what just a few people who have tried it are saying:

"This oil is simply amazing! I have not found a herb that clears the lymphatics and intestines so clearly and in such a gentle way."

A Pouget, Medical Herbalist

"I suffer from eczema. When it comes out I use your oil and it clears up very quickly."

Abdullah, Cyprus

"I had a flare up and your Nigella Sativa oil cleared it. Amazing!"

D Roper , London
Nigella Sativa comes from the Ranunculaceae,The Buttercup Family

There are around 1800 species in this family, which is found mainly in the colder regions of the world. Most of them are well-known wild flowers or garden flowers, including Buttercups, Anemones, Delphiniums, Aquilegias and Clematis. Some species, particularly Aconitum, are poisonous. Nearly all members of the family are herbaceous, with Clematis being the only woody species.

Nigella seeds are small, matte-black grains with a rough surface and an oily white interior. They are roughly triangulate, 1 1/2 - 3 mm (1/16 to 1/8 in ) long. They are similar to onion seeds.

Relatives to Nigella sativa are Nigella arvensis, Nigella ciliaris, Nigella damascena, Nigella hispanica, Nigella integrifolia, Nigella nigellastrum, Nigella orientalis. The Nigella sativa seed is used as a spice. Nigella sativa has a pungent bitter taste and smell. It is used primarily in confectionary and foods.


Diabetes Nutritional Supplements May Help Control Blood Sugar Levels
Dealing with diabetes can be controlled with correct food supplements, with proper diet and regular physical activity.

There are special additions that have been demonstrated in laboratory tests in order to stabilize blood sugar levels. Some of these supplements for diabetes are enzymes that aid digestion or improve glucose metabolism. Others are minerals such as calcium, magnesium and chromium, which are often lacking in the diet are. And other herbs and vegetables.

Herbs and vegetables has long been used by aborigines for the treatment of various diseases and symptoms. Sometimes these drugs are very effective. You can somewhat 'controversial and should not be expected that the position of the modern take drugs, but to integrate them "modern medical treatments. In someCases, people who begin taking herbal remedies are able to reduce their medication, of course, with the advice of his doctor. The herbs and herbal ingredients are included in some supplements for diabetes, because they have been historically used to treat the condition and why the modern evaluation has shown that they are to manage the condition, today may be useful.

Banaba is in some of the best diabetes supplements found. This is a plant that is native to southern Asia and has a history of traditionused to help people control their blood glucose levels. Laboratory tests have shown that lowering Banaba added in the diet of diabetic rats glucose levels in the blood and the leaves seem to contribute to weight loss in obese mice. Studies in 1999 and 2001 found that the extract of Banaba can help control blood sugar levels and possibly help you lose weight. Researchers have suggested that clinical trials that a people "true" that were in order. But clinical are quite expensive and most are sponsored by pharmaceutical companies. Most pharmaceutical companies have no interest in a natural substance, such as extract of Banaba, because it can not be patented. Therefore, clinical studies have never been, but Banaba extract has been launched in some dietary supplements for the treatment of diabetes were found.

Bitter Melon is another plant that has shown promise in the laboratory. Bitter melon tea is still used today in the Philippines, especially among the poor, in order to maintain control> The levels of blood sugar. In Ayurvedic medicine, practiced throughout the world in India and different countries, it is recommended as one of diabetes, dietary supplements and as a complement to other forms of treatment. Glycemic control should be carefully monitored when diabetic food supplement containing bitter melon in order to avoid a dangerous drop in blood sugar.

Black or Nigella sativa seed extract is used as a cure all in some countries. ModernResearch on black extract in the treatment of diabetes is temporary. But research shows so far that can reduce high blood sugar and increase the antioxidant activity, possibly preventing the complications of uncontrolled diabetes type II. Referred for further and more detailed information about this plant and other natural supplements for diabetes, please visit the Diabetes Information Guide.

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Research on Intestines

Effects of Nigella sativa Seeds on Intestinal Smooth Muscle
Author: Mahmoud B. Aqel a
Affiliation: a College of Medicine, The University of Jordan, Amman, Jordan

DOI: 10.3109/13880209309082918
Publication Frequency: 12 issues per year
Published in: Pharmaceutical Biology, Volume 31, Issue 1 1993 , pages 55 - 60
Subject: Natural Products;
Formats available: PDF (English)
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The spasmolytic effects of an ethanol extract and the volatile oil of Nigella sativa seeds were tested in vitro using isolated segments of rabbit jejunum. The ethanol extract and volatile oil inhibited spontaneous movements of the rabbit jejunum. Also, the volatile oil inhibited contractions of the rabbit jejunum which were induced by high potasium (K+) solution or acetylcholine. This inhibition was dose-dependent, reversible and not affected by the addition of calcium to the organ bath. These data suggest that the plant seed has an antispasmodic effect, possibly due to a calcium antagonistic activity.

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Cure of worms in dogs

Title: Prevalence and therapy of ancylostomiasis in dogs with Nigella sativa (Kalongi) and Saussurea lappa (Qust-e-shireen).
Personal Authors: Jahangir, M., Maqbool, A., Tanveer, A., Mahfooz, A.
Author Affiliation: Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan.
Editors: No editors
Document Title: Haryana Veterinarian

In first part of this study, 250 dogs in Pakistan were examined for the presence of ancylostomiasis [date not given]. Faecal examination confirmed ancylostomiasis in 67 (26.8%) dogs. A higher prevalence was noticed in puppies than in adults. In 8 controlled experiments, 48 dogs were used to compare the efficacy of Nigella sativa seeds, Saussurea lappa roots and pyrantel pamoate against Ancylostoma spp. Efficacy was quantified by determining the difference of eggs per gram of faeces (EPG) during pre- and posttreatment. It was shown that N. sativa seeds, after a single dose of 250, 300 and 500 mg/kg body weight, reduced EPG by 62.9, 80.9 and 89.6%, respectively. S. lappa roots at of 200, 250 and 300 mg/kg body weight was 40.5, 66.5 and 79.9% effective against Ancylostoma, respectively, while pyrantel pamoate at 10 mg/kg body weight was 100% effective. The efficacy order was pyrantel pamoate>N. sativa>S. lappa. No side effects were caused by any of the drugs of plant origin.

Publisher: College of Veterinary Sciences, Haryana Agricultural University

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Black seed oil can help pancreatic cancer

Wellness Watch/Energy Times June 2009

Herb May Inhibit Pancreatic Cancer
The fact that this disease tends to kill so quickly after diagnosis makes cancer of the pancreas difficult to study compared with other malignancies. It is generally found only after it has spread to other organs; scientists are currently trying to find the genetic clues that would allow earlier diagnosis.
The risk of developing pancreatic cancer is somewhat greater among people with a family history of the disease or an inflammatory condition called chronic pancreatitis. But an extract taken from Nigella sativa, the "black seed" used widely in Middle Eastern cooking and traditional healing, has lowered levels of the inflammatory substances linked to pancreatic cancer. Scientists at the Kimmel Cancer Center at Thomas Jefferson University found that thymoquinone, found in black seed oil, was also able to shrink tumors in 67% in animals. These findings were presented at the American Association for Cancer Research's 2009 annual meeting.

Black seed is available in two blends at

This blog contains material intended for informational purposes only. The statements made have not been evaluated nor approved by the FDA. Any dietary changes and/or product(s) mentioned should not be used to diagnose, treat, cure or prevent disease. Consult your health care provider before making changes to your health care regimen - particularly if you are taking medication(s), are pregnant, trying to get pregnant, nursing, or if you have any other health condition - before making any dietary changes, using any products mentioned or applying any information contained herein.