The Many Health Benefits Of Black Seed Oil

By: tishbite Home
Health
I am more than convinced that black seed oil is one of the best essential oils that money can buy. The reason that I say this is because this oil can be taken internally for many of its health benefits. It can also be applied to the skin in order to take advantage of the many external benefits that it gives. Black seed oil is an excellent cure all and when one tablespoon is taken per day it will pay out huge dividends to your health.

When you purchase black seed oil you need to purchase the pure product in order to get the full advantage of its healthful benefits. The oil is black in color so keep in mind that it will give you a tan when you use it each day. It has just about as much potency as aloe vera oil when it is used on the skin. It is an excellent product for skin cell regeneration because it contains so many anti oxidizing chemicals. Black seed oil fights the free radicals which attack and damages skin cells. This makes it an excellent product for recovery from exercise or even for daily use. It takes the free radicals away from the cells where they are flushed away in the blood stream.

Black seed oil is a good anti bacterial product because of its germ fighting effects. This makes it good for fighting infection or for general topical use. You can use it to fight acne, dandruff, and other skin ailments. It is useful for application to cuts, scrapes, and burns. I use it sometimes when I shave to guard against the effects of the razor and it really works wonders for my sensitive skin. I dont suffer from rashes and razor bumps when I use it. I dont apply it every day because my skin is too sensitive for me to shave each day. It is also useful for treating burns because it contains many nutrients which feed damaged skin cells.

Black seed oil is wonderful when it is taken internally. It works wonderfully when taken for nausea and upset stomach. It also stimulates the digestive tract. Black seed oil is good for insomnia and works well when taken with a hot beverage before bed.

Another benefit of this product is that it can be used to help relieve muscle cramps and spasms which plague so many of us as we get older. The relaxing effects of this product promotes rest and healing.

Black seed oil also helps to regulate the high blood pressure which is so prevalent among older people. It also fights internal infections the same way that it fights infections of the skin so it is an excellent antibiotic. Its healing and regenerating properties relieves the symptoms of flu and fever, and brings relief to those who suffer from allergies.

This is one of the two or three essential oils that we offer which would be good to keep on hand at all times. Take it daily to prevent a host of illnesses and symptoms. We have written many articles on the wonders of this product. We cant adequately cover all of its uses here but if you continue to follow us we will add articles in the future. Eventually we will be able to make an adequate compilation on the healthful benefits of this product. Fragrance Oil Express

Article Source: http://www.articlesnatch.com/

Where to buy Black seed oil


http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com/

"Health Properties of Black Seed Oil"

 by ben master
As I was studying the range of anti inflammatory herbs out there, I came across an interesting oil I hadn't heard of before, black seed oil, also known as black cumin. Like most healthy natural oils, black seed oil has been used for a very long time in other cultures, but has only recently started to be discovered by westerners. Black seed oil has had a long history of 1400 years of use, and traditionally it was used to help a wide variety of ailments, from simple things like nervousness to serious things like heart disease.

Black seed oil seems to be especially effective against respiratory ailments because it has an active agent that calms the nerves and is antispasmatic, and it also contains an active ingredient that helps support the bronchial tubes. But the reason why I'm intrigued by it is because it acts both as a detoxifier as well as an anti inflammatory. Those are two benefits which I've been researching heavily in recent days. Not only that, but black seed oil contains over 100 different nutrients that are all beneficial to the human body. This too I like, since one of my quests is to take as few supplements as possible.

Where to buy Black seed oil


http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//

Acne and the Healing Power of Black Seed Oil

My teenage daughter was suffering from acne so badly, that I felt, I really needed to do something to find out what the alternatives are after trying all kinds of creams and products that were advertised on TV. Since I am a big believer in the natural healing power of certain herbs I started doing my researches on the one herb I was taking all along for myself. It's Black Seed Oil. It takes care of a lot of conditions people are suffering from. So I found out that acne was on the top of the list as treating it naturally from inside out by balancing your entire body chemistry.

She started taking the oil and after a few months we can see how her skin is slowly clearing up. Of course it doesn't happen overnight, but we definitely see a major improvement. Especially those bigger cysts started to heal off and what's left are just some tiny pimples that are also starting to clear.

Black Seed Oil called Black Cumin Oil is special as a natural treatment for acne as it strengthens the immune system.
Black cumin should be taken orally 2-3 times a day in a teaspoon of oil or 2-3 capsules. It is important to make sure that the oil is pure cold pressed black seed oil.



For a more intensive treatment of acne, you can additionally use the oil topically.
Add 2 teaspoons of black seed oil to a bowl of hot water and then put face over the bowl with a towel covering the head and the bowl.
Depending on the severity of the condition herbal remedies such as black seed oil work naturally.



As a natural home remedy for acne this will take time to heal and may need to be administered for 1-2 weeks before any results can be seen.
There are 2 different forms of Black Seed Oil that are the most effective. You can either get the cold pressed oil as the liquid version or go for the more easier way by taking 2-3 gel capsules a day. Both ways the oil is easy to take and it will help you to balance your overall body chemistry and health in general.

Read about all the health benefits and conditions that can be treated with the healing power of Black Seed (also called Black Cumin Oil). Unfortunately, in this country this oil hasn't become very popular yet while it has been known as a cure for all these many different conditions for thousand of years. Even the old Egyptians knew about the power of those hundreds of natural ingredients that give the body the strength to fight off a lot of nasty conditions. Until the vitamin stores will finally put this amazing herb in their shelves you can only order it online. But make sure it is cold pressed and pure. The page below has a lot of information about the strength of this oil.

Article Source: http://EzineArticles.com/6126500

Where to buy Black seed oil


http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//

The In Vivo Antidiabetic Activity of Nigella sativa

Research Article


The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content

Ali Benhaddou-Andaloussi,1,2 Louis Martineau,1,2 Tri Vuong,1,2 Bouchra Meddah,3 Padma Madiraju,1,2 Abdellatif Settaf,3 and Pierre S. Haddad1,2

1Department of Pharmacology and Montreal Diabetes Research Center, Université de Montréal, Montréal, QC, H3C 3J7, Canada

2Institut des Nutraceutiques et des Aliments Fonctionnels, Laval University, Quebec City, QC, G1K7P4, Canada

3Research Team in Pharmacokinetics, Laboratory of Pharmacology and Toxicology, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat-Souissi, Morocco

Received 5 July 2010; Revised 26 January 2011; Accepted 15 February 2011

Copyright © 2011 Ali Benhaddou-Andaloussi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The antidiabetic effect of N. sativa seed ethanol extract (NSE) was assessed in Meriones shawi after development of diabetes. Meriones shawi were divided randomly into four groups: normal control, diabetic control, diabetic treated with NSE (2 g eq plant/kg) or with metformin (300 mg/kg) positive control, both administered by daily intragastric gavage for 4 weeks. Glycaemia and body weight were evaluated weekly. At study's end, an Oral Glucose Tolerance Test (OGTT) was performed to estimate insulin sensitivity. Upon sacrifice, plasma lipid profile, insulin, leptin, and adiponectin levels were assessed. ACC phosphorylation and Glut4 protein content were determined in liver and skeletal muscle. NSE animals showed a progressive normalization of glycaemia, albeit slower than that of metformin controls. Moreover, NSE increased insulinemia and HDL-cholesterol, compared to diabetic controls. Leptin and adiponectin were unchanged. NSE treatment decreased OGTT and tended to decrease liver and muscle triglyceride content. NSE stimulated muscle and liver ACC phosphorylation and increased muscle Glut4. These results confirm NSE's previously reported hypoglycaemic and hypolipidemic activity. More significantly, our data demonstrate that in vivo treatment with NSE exerts an insulin-sensitizing action by enhancing ACC phosphorylation, a major component of the insulin-independent AMPK signaling pathway, and by enhancing muscle Glut4 expression.

Where to buy Black seed oil


http://www.theblessedseed.com/
http://www.regenerativenutrition.com/
http://www.taylor-jackson.com//

Black Cumin the Best Choice for Radiation Exposure

Radiation exposure solutions may amount to a simple capsule called Black Cumin. If you have ever looked for a solution to help you avoid any complications from radiation exposure, then Nigella sativa should be top on your list.

With the recent problems in Japan many are told to take iodine or kep, but iodine comes with many side effects. I recently inquired about iodine for my mom and son and found out that anyone taking pharmaceutical medicines could not take iodine except under guarded conditions which are monitored by a physician. My mom has recent heart problems and my son is currently experiencing eye problems and will have his second surgery in two weeks.
When I checked with a man who sells high grade iodine, he suggested that I look for another alternative. Iodine is only good for the thyroid, so what happens to those who have multiple problems and a history of cancer, like my son. My son had stomach cancer a few years ago.

The more I read, the more I decided that black cumin was my best choice. Read this information on radiation and black cumin:

Immune System Benefits

There is convincing scientific evidence stating that the consumption of black cumin seeds can have benefits for the immune system. A study performed by M.E. Assayed for the Department of Forensic Medicine and Toxicology at Menoufiya University-Sadat City Branch in Egypt evaluated the use of black cumin seeds on the immune system of study subjects who were exposed to gamma radiation. The results of the study revealed that study subjects who were administered black seed oil orally encountered fewer immune system disorders as a result of the radiation exposure than study subjects who were left untreated. The results of this study indicate the oils from black cumin seeds offer immune system protection from radiation exposure.
Read more: http://www.livestrong.com/article/338966-black-cumin-seed-benefits/#ixzz1IDUG96YN
Once you build up the immune system with black cumin oil you are able to handle the problems of gamma radiation exposure, in most cases. Needless to say there will always be someone who does not fit the mold.

So for me I ordered the black cumin capsules for my mom and son. Black cumin protects the whole body not just the thyroid.

Read my book: Everything you ever wanted to know about Black Cumin

Posted by Barbi Trejo at 10:51 Email This

Labels: black cumin for radiation exposure, black cumin solves japan radiation problem

DETECTION OF THE ANTIBACTERIAL EFFECT OF NIGELLA SATIVA GROUND SEEDS WITH WATER

H. Bakathir, N. A. Abbas

Abstract

Nigella Sativa (NS) seeds have been used for medicinal purposes for centuries both as herbs and its oil. In Islam it is regarded as one of the greatest forms of healing medicine included in the medicine of prophet Mohammed. Huge number of studies have been carried out in recent years on the pharmacological effects of these seeds and also the possible relationship with their constituents. A number of these investigations emphasized the antimicrobial effect of them by using different extracts. In our study we have tried to use the normal human mechanism in digestion by using the ground seeds. A modified paper disc diffusion method was used to test the antibacterial effect of NS seeds. Clear inhibition of the growth of Staphylococcus aureus was observed by concentration of 300mg/ml with distilled water (D.W.) as control , this inhibition was confirmed by using the positive control Azithromycin. The inhibition obtained was higher with Nigella sativa ground seeds from Hadramout (HNSGS) than with Nigella sativa ground seeds from Ethiopia (ENSGS). No inhibition was found in the growth of E.Coli and Enterobacter. This was emphasized by using the positive control Ciprofloxacin. The positive inhibition may be attributed to the two important active ingredients of NS, Thymoquinone and melanin .


Full Text: FullText.PDF

Nigella Seed - Black Seed, Sanouj, Black Cumin

Definition: Standard Arabic: حبة البركة or حبة السوداء


Nigella seeds (black seeds) are cultivated domestically in Morocco from the Nigella sativa plant and used as a spice, condiment and medicinal treatment. They have a slightly bitter and peppery quality with a mild oregano-like flavor. The seeds should be lightly toasted before using whole, crushed or ground.

In Morocco nigella is commonly referred to as sanouj. It is found in bread recipes such as Khobz Mzaweq; and as a mild seasoning in certain dishes, such as Chicken Tagine with Nigella Seeds. Nigella is also used in Indian, Middle Eastern and some European cooking.

In standard Arabic nigella is known by several names, including habbah sauda and habbah al-baraka. In various parts of the English speaking world, nigella seed is also known as black cumin, black sesame, black caraway, and black onion seed, although these names are often cited as misleading.
An Islamic hadith extols nigella as being "a cure for every disease except death." Indeed, traditional medicinal uses of black seed are extensive, including the treatment of skin conditions, respiratory infections, intestinal disorders and parasites, headaches, toothaches and more. Nigella helps promote lactation in nursing mothers and uterine contractions during labor, works as an insect repellent and is known to have anti-inflammatory, antibacterial and antioxidant properties. Studies suggest it also inhibits cancer cell progression and boosts the immune system.


Alternate Spellings: sanouz

Black Seed Oil (Nigella Sativa) And Its Disease Preventing Effects

- by HealthyMuslim



This is from an article that has been attributed to a Hans Wagner and was published on the web, appearing to be a translation from a German source. It summarizes many of the findings from scientific research papers and studies that we have already looked at. As it already contains most of the information we’ve decided to reproduce it here with corrections to some typos and just one or two minor edits.

It should be mentioned that the black seed oil has a rich composition of proteins,minerals, carbohydrates and fats. Almost all of its fat content is in the form ofomega-3 and omega-6 fatty acids – which are very important for good overallhealth and a sound immune system. It also has around 15 amino acids, the building blocks of protein, 9 of which are the essential amino acids.

On to the article:

Recently scientists around the world have confirmed the anti-bacterial and anti-mycotic effects of black seed oil. Healthpractitioners in various countries around the world are using theoil against inflammation of all sorts as well as fungi infections. Even a remarkable reduction of blood sugar levels has been found by scientists. Black seed extracts have been found help to stimulate bone marrow and immune cells, so writes the scientists of the cancer Immuno-Biology Laboratory and adding that it raises the interferon production, protects normal cells against cell destroying effects of viruses, destroys tumor cells and raises the number of anti-bodies producing B cells.

All these functions make the black seed oil the ideal candidate for the prevention and treatment of cancer. Scientists are now busy finding the effects of the black seed oil in regard to various other human health conditions. Dr.Med.Peter Schleicher, an immunologist, in Munich who in 1986 happened to be nominated the youngest member of the World Academy of Scientists, examined black seed oil in his institute to find new therapies forchronic illness and its effect. His findings are identical to those in previous studies by earlier researchers.

Schleicher says, by using black seed oil, valuable unsaturatedfatty acids, for example Linoleic and Gamma-linolenic acids, get into the organism. By that it is possible to reach a synthesis of important immune regulating substances derived from Prostaglandin E1. Linoleic acid stabilizes the cell membranes and Prostaglandin has the effect of inhibiting inflammation. By that the immune reactions are stopped which cause the illnesses and which otherwise could be the start of many many chronic illnesses like acne and hay-fever right up to cancer. In addition, the excessive T-cell function of the person suffering fromallergies are stabilized through the substance in black seed oiland the abnormally rising immune reactions through suppressed anti-bodies. The excessive immune system is normalized and the large cell degranulation decreased.


Studies also testify that an immune system which has gone wrong can again be regulated by the strong effect of the oil. Schleicher, meanwhile, has tested the effect of the oil on 600 patients. As a result he confirms the cure for allergies at about 70% of the patients. Amongst them are allergies against pollen and dust, acne and neuro-dermatological illnesses, asthmapatients, etc.. who generally have a weak resistance and are prone to suffer from infections. For that reason Dr.Schleicher in Munich is going to include the oil with his preventative treatment against colds and influenza.


In the Middle East and South Asia, this oil has been used for thousands of years as a remedy for all sorts of allergies,inflammation and menstruation problems, boosting moral, depression; but especially against bronchitis, asthma and neuro-dermatitis as well as poor digestion and even impotency. The Prophet Mohammad [sallallaahu alayhi wa sallam] stated in his “Hadith” that black seed oil cures every illness except death. No wonder then that a little bottle of the oil was even found in the tomb of the legendary Pharaoh Tutankhamen!

In the West the effect of the oil has been used for a long time against wind, dysentery, stomach and lung disease, jaundice, diuretic problems and to increase nursing mother’s milk. Due to the triumphant advances in chemistry the oil has been forgotten until recently. According to Dr. Schleicher the reason why this oilis so exceptional is that its component parts act in unison to produce an optimum effect for so many complaints. But one has to make sure that only the pure and tested oil is being used.

Schleicher’s colleagues have reacted very positively after the publication about his success with patients who have used theoil. Professor G. Rietmuller, Director of Institute for immunology at the University of Munich believes that this plant extract works positively on the immune system and could be used as a bio-regulator. Professor Michael Meurer of the Dermatology Clinic in Munich has for a long time been convinced about the success of this oil. From his experience the oil help stop inflammation and helps with neurodermitis.

At the International cancer Congress in New Delhi last Autumn the anti-tumor effect of black cumin oil has been introduced to many scientists and doctors.

Middle Eastern Beauty, Readily Available on Atlantic Avenue

From Bond Street to Third Avenue, natural and organic beauty options

Essential oils behind the counter at Al Firdous.


First, we took you on a tour of the Middle Eastern food shops on Atlantic Avenue. This time, come along for a trip to the other end of western Atlantic to complete the Middle Eastern shopping experience on one of Brooklyn's main drags.

Before you reach Atlantic Terminal and the end of artsy and interesting Atlantic Ave., you'll find a variety of Middle Eastern beauty and clothing stores and bookshops. Quieter than their foodie counterparts, the stores are great for browsing at length.

At Anwaar Co., between Bond and Nevins, you'll find more black seed beauty products than one could ever imagine. The quiet store is a good place to browse solitarily without being bothered. A friendly woman in a black hijab stays behind the counter at the bright, neat shop.

If you’re looking for a purely consumer experience, Anwaar offers up an incredible array of shea butter products, natural and organic hair and body care, and a myriad of essential oils line almost an entire wall on one side of the store. Decorative bottles for these scents are stored under a glass case. Most of the black seed items are topical, but there are many to choose.

(For the uninitiated -- Muhammad was said to have claimed that black seed, the scientific name of which is nigella sativa, is “a cure for all diseases except death.”)

A little farther east on Atlantic is Al Firdous. This notions and cosmetics shop is smaller than Anwaar, just as quiet, and has a more varied selection of products. It’s manned by the Bangladeshi owner’s younger brother, Alamin, who sports a long beard and wears a taqiyah, albeit with jeans and sneakers. He's shy but quite knowledgeable.

Al Firdous has the air of being undiscovered by the neighborhood. Visit soon in order to get all the attention you need.
Alamin explained that black seed -- which is prominently advertised on Al Firdous’ awning -- is one of the store’s “top of the line sellers” in ingestible oil form. Several shelves are devoted to the purported cure-all, including the jars of the plain seeds themselves, which can be added to yogurt or cereal.

Toward the back of the shop are shelves with big lumpy, black, paper-wrapped packages called “African Soap,” sold by weight. Though it looks like a bulk item, waiting to be sliced and measured, Alamin said “people buy the whole thing.”

In addition to the soap, there are quart containers of shea butter piled on the floor, a variety of homeopathic remedies stocked along the walls, and the ubiquitous, colorful essential oil bottles behind the counter. The scents range from rose to “Halston,” with other knockoffs like CK One sneaked in there, too. Alamin pointed out the oils’ various prices “get better the more you buy.”

Dar-us-Salam Bookstore is right next door to Al Firdous, and though it specializes in books with titles like The Qur’an and Modern Science: Compatible or Incompatible?, one can also purchase toothbrushes and halal soap here.

Up at the counter is a stack of Sisters: The Magazine For Fabulous Muslim Women. The store extends through several rooms and is incredibly crowded with books and DVDs -- it seems the extra stock is piled in the middle of some of the main space, there are so many books.

On a recent snowy weekday, the shop was quiet, and staffed by an appropriately bookish-looking young man named Faisal. The shop appears to be a community hang-out, of sorts. A couple of reticent men, who didn’t seem to be either working or shopping, stood around the front counter and very occasionally spoke in Arabic with Faisal.

As at Al Firdous and Anwaar Co., numerous black seed products were on hand, and Faisal said “they’re for the immune system, but they’re not medicinal.”

In the back there is an assortment of djellaba (long, loose-fitting robes) and in another room, a glass case with beaded and embroidered women’s leather slippers. Faisal said all the books are from the Middle East -- none are published in the U.S.

If you haven't already, stop by one or all of these local shops. The experience will give you something to take home, even if you don't buy anything.

Have you visited any of these shops? Will you now?

Black Seed Reduces Ulcer Index

Nigella sativa seeds was effective in reducing the ulcer index

Ulcers and Gastroprotective



An animal study suggested that the aqueous extract of Nigella sativa seeds was effective in reducing the ulcer index (induced by aspirin) by about 36%. Moreover, the treatment reduced the peptic activity and acid production. Another study found that the administration of black seed oil for 2 weeks increased gastric mucin and glutathione content, and reduced histamine content. This is in line with earlier studies that have suggested a cytoprotective action of black seed oil, and lends some credence to the folkloric use of the oil as an antiulcer agent. A different study discovered a single oral dose of black seed could partly reduce the ulcer index and promote healing of gastric lesions induced by acute intake of alcohol. Additionally, black seed significantly decreased the gastric MDA content while it increased the gastric level of glutathione compared to alcohol. The gastric activities of both antioxidant enzymes superoxide dismutase (SOD) and glutathione-S-transferase (GST) were markedly elevated following administration of black seed. Likewise, thymoquinone protected against the ulcerating effect of alcohol and mitigated most of the biochemical adverse effects induced by alcohol in gastric mucosa, but to a lesser extent than whole black seed. Researchers also hypothesized that thymoquinone's antihistaminic effect could play a role in preventing gastric injury as an antihistaminic effect has been shown to be an important preventive mechanism against gastric injury. Given its safety profile, don't be surprised if thymoquinone will be a choice of treatment for gastric ulcers in the near future.









--------------------------------------------------------------------------------



Akhtar AH, Ahmad KD, Gilani SN, et al. Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats. Fitoterapia 1996; 38: 195–199.



El-Abhar HS, Abdallah DM, Saleh S. Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats. J Ethnopharmacol. 2003 Feb;84(2-3):251-8. El-Dakhakhny M, Barakat M, El-Halim MA, et al. Effects of Nigella sativa oil on gastric secretion and ethanol induced ulcer in rats. J Ethnopharmacol. 2000 Sep;72(1-2):299-304.



El-Kadi A, Kandil O, Tabuni AM. Nigella sativa cell-mediated immunity. Arch AIDS Res. 1987; 1: 232–233.



Kahraman A, Erkasap N, Köken T, et al. The antioxidative and antihistaminic properties of quercetin in ethanol-induced gastric lesions. Toxicology. 2003 Feb 1;183(1-3):133-42.



Kanter M, Coskun O, Uysal H. The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage. Arch Toxicol. 2006 Apr;80(4):217-24.



Kanter M, Demir H, Karakaya C, et al. Gastroprotective activity of Nigella sativa L oil and its constituent,thymoquinone against acute alcohol-induced gastric mucosal injury in rats. World J Gastroenterol. 2005 Nov 14;11(42):6662-6.

Black Seed Improved Seizure Control

Black Seed Improved Seizure Control


A recent study found black seed oil has anticonvulsant effects and improved seizure control in children suffering from refractory epilepsy

Nearly 15% of childhood epilepsy cases are resistant to treatment. Many of the drugs used to treat epilepsy produce unwanted side effects or are capable of producing serious adverse events. When epilepsy remains uncontrolled, it is termed refractory or pharmacoresistant. A recent study found black seed oil has anticonvulsant effects and improved seizure control in children suffering from refractory epilepsy. Earlier animal studies have also demonstrated the anticonvulsant effects of thymoquinone. Researchers hypothesized that thymoquinone may have anticonvulsant activity in petit mal epilepsy probably through an opioid receptor-mediated increase in GABAergic tone. They have also suggested black seed's potent antioxidant properties may be responsible for preventing seizures as well.





Akhondian J, Parsa A, Rakhshande H. The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures. Med Sci Monit. 2007 Dec;13(12):CR555-9.



Hosseinzadeh H, Parvardeh S, Nassiri-Asl M, et al. Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats. Med Sci Monit. 2005 Apr;11(4):BR106-10.



Hosseinzadeh H, Parvardeh S. Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice. Phytomedicine. 2004 Jan;11(1):56-64.



Ilhan A, Gurel A, Armutcu F, et al. Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice. Neuropharmacology. 2005 Sep;49(4):456-64.



Verhelst H, Boon P, Buyse G, et al. Steroids in intractable childhood epilepsy: clinical experience and review of the literature. Seizure. 2005 Sep;14(6):412-21.






TESTIMONIALS



After taking the gel tabs for only a few weeks, I noticed several changes.

After taking the gel tabs for only a few weeks, I noticed several changes. My cholesterol that had been high was now under control. I put away my prescription for a well known allergy medication. And so far... flu season has passed me by.





Martha A.

Plantation, FL

Black Seed Antiparasitic Properties

Black Seed Antiparasitic Properties


Black seed oil has been shown to possess antiparasitic properties comparable to those of some of the leading pharmaceuticals

Black seed oil has been shown to possess antiparasitic properties comparable to those of some of the leading pharmaceuticals. In one study, black seed oil was effective in reducing the number of Schistosoma mansoni worms in the liver and decreased the total number of ova deposited in both the liver and the intestine. Furthermore, it increased the number of dead ova in the intestinal wall and markedly reduced the granuloma diameters.



Administration of black seed oil concomitantly with the leading flatworm pharmaceutical, lowered further the number of dead ova than was observed when the drug was given alone, indicating that the plant oil potentiates the action of the drug.









--------------------------------------------------------------------------------



Agarwal R, Kharya MD, Shrivastava R. Antimicrobial & anthelmintic activities of the essential oil of Nigella sativa Linn. Indian J Exp Biol. 1979 Nov;17(11):1264-5.



Mahmoud MR, El-Abhar HS, Saleh S. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. J Ethnopharmacol. 2002 Jan;79(1):1-11.


TESTIMONIALS



I have suffered from allergies all my life

"I have suffered from allergies all my life. I took a small sample from a friend during a bad attack. The next morning I rushed to buy my own supply. It really worked a miracle in me within 24 hours.

Brunnie T.

Fort Lauderdale, FL

Traditional Herbal Medicine Kills Pancreatic Cancer Cells

Traditional Herbal Medicine Kills Pancreatic Cancer Cells


Traditional Herbal Medicine Kills Pancreatic Cancer Cells, Kimmel Cancer Center at Jefferson Researchers Report



(PHILADELPHIA) - An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of Nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death.



While the studies are in the early stages, the findings suggest that thymoquinone could eventually have some use as a preventative strategy in patients who have gone through surgery and chemotherapy or in individuals who are at a high risk of developing cancer.



According to Hwyda Arafat, M.D., Ph.D., associate professor of Surgery at Jefferson Medical College of Thomas Jefferson University, Nigella Sativa helps treat a broad array of diseases, including some immune and inflammatory disorders. Previous studies also have shown anticancer activity in prostate and colon cancers, as well as antioxidant and anti-inflammatory effects.



Using a human pancreatic cancer cell line, she and her team found that adding thymoquinone killed approximately 80 percent of the cancer cells. They demonstrated that thymoquinone triggered programmed cell death in the cells, and that a number of important genes, including p53, Bax, bcl-2 and p21, were affected. The researchers found that expression of p53, a tumor suppressor gene, and Bax, a gene that promotes programmed cell death, was increased, while bcl-2, which blocks such cell death, was decreased. The p21 gene, which is involved in the regulation of different phases of the cell cycle, was substantially increased. She presents her findings May 18 at the Digestive Disease Week in San Diego.



Dr. Arafat and her co-workers also found that thymoquinone caused "epigenetic" changes in pancreatic cancer cells, modifying the cells' DNA. She explains that these changes involve adding acetyl groups to the DNA structure, specifically to blocks of proteins called histones. This "acetylation" process can be important for genes to be read and translated into proteins. In this case, it could involve the genes that are key to initiating programmed cell death. "We looked at the status of the histones and found surprisingly that thymoquinone increased the acetylation process," Dr. Arafat says. "We never anticipated that."



At the same time, adding thymoquinone to pancreatic cancer cells reduced the production and activity of enzymes called histone deacetylases (HDACs), which remove the acetyl groups from the histone proteins, halting the gene transcription process. Dr. Arafat notes that HDAC inhibitors are a "hot" new class of drugs that interfere with the function of histone deacetylases, and is being studied as a treatment for cancer and neurodegenerative diseases. Finding that thymoquinone functions as an HDAC inhibitor, she says, "was very remarkable and really exciting."



Pancreatic cancer, the fourth-leading cause of cancer death in this country, takes some 34,000 lives a year. The disease frequently is detected after it has spread and only 4 percent of individuals with pancreatic cancer live for five years after diagnosis.









--------------------------------------------------------------------------------



TESTIMONIALS



I started taking the capsules this year during the cold and flu season to help my immune system.

I started taking the capsules this year during the cold and flu season to help my immune system. For several weeks my co-workers were getting sick one after another, but I felt healthier than usual. I was amazed at how much stronger I felt! Eventually I did catch the cough/cold that had been going around (stress and extended lack of sleep will do that to you, no matter how strong your immunity). However, I got better at least 5 times faster than my co-workers with the same illness -- I only had to take 1 sick day. With a high-stress job, this is a supplement I don't want to go without. The other benefits (clearing skin, improving hair) are a nice bonus, too!



Amina

Alexandria, Virginia

Black Seed Helps With Impotence

Black Seed Helps With Impotence


Today, Science has proven Black Seed Oil 's effectiveness as an immune system booster.

A seed few people in the U.S. have heard of has a fascinating history and is used by a large portion of the world's population. References to this seed can be found in some of the oldest religious and medical texts. It is called Black Seed. Black Seed (Nigella sativa) is a tiny seed from an herbaceous annual, which reaches a height of twelve to eighteen inches. It is believed to be indigenous to the Mediterranean but is cultivated in other parts of the world including North Africa, the Middle East and parts of Asia. The common English name for Nigella sativa is Love in a Mist. It is also called Black Cumin.



History of Black Seed

Black Seed was discovered in the tomb of the legendary Egyptian Pharaoh Tutankhamen, implying that it played an important role in ancient Egyptian practices. Although its exact role in Egyptian culture is not known, we do know that items entombed with a king were carefully selected to assist him in the afterlife. The earliest written reference to black seed is found in the book of Isaiah in the Old Testament: (Isaiah 28:25,27 NKJV).



Traditionally Black Seed has been used for a variety of ailments including bronchitis, asthma, rheumatism and related inflammatory conditions, increasing milk production in nursing mothers, digestive and eliminative disturbances, parasite infection and supporting immunity. Its oil is used to treat skin conditions such as eczema and boils and is used topically to treat cold symptoms. The classic text Medicines of the Prophet lists as many as fifty illnesses for which Black Seed has effective healing qualities.



Because of its complex chemical structure — it has over one hundred active ingredients — black cumin has positive effects on the respiratory, immune, circulatory, digestive, and urinary systems. It is potentially effective against asthma, stomach ailments, and numerous skin conditions, ranging from acne to psoriasis. Its many uses has earned it the popular title "Seed of Blessing".



Modern Research

Over 150 research papers on Black Seed have been published in recent times confirming many of the healing properties traditionally attributed to Black Seed.



In 1987, a study conducted at I.I.M.E.R. Panama City, Florida verified the immune-supporting action of Black Seed. Two randomized groups of volunteers received one-gram of Black Seed capsules twice daily or a placebo. A complete lymphocyte count carried out before and after four weeks of administration revealed that the majority of subjects who took Black Seed displayed a 72% increase in helper-to-suppressor T-cell ratio as well as an increase in NK (natural killer) cell functional activity.



In the field of AIDS research, human clinical trials conducted at the Department of Biological and Medical Research Center in Riyadh, Saudi Arabia (1997) showed that Black Seed enhanced the ratio between helper T-cell by 55% with a 30% enhancement of NK cell activity. These findings suggest that Black Seed could play an important role in the treatment of cancer, AIDS, and other immune deficiency states.



In 1997 a study undertaken on the anti-cancer activity of the Black Seed undertaken at the International Immuno-Biology Research Laboratory, South Carolina concluded, "the activity of NS (Black Seed) blocked the tumor growth and dissemination in metastasis and have remarkable promises for clinical use."



Histamine is a substance released by body tissues, which often causes allergic reactions and is associated with conditions such as bronchial asthma. In 1960, scientists discovered that a substance called Nigellone (dimer dithymoquinone) isolated from Black Seed's volatile oil suppressed asthma symptoms in a majority of patients when given orally.



As early as 1960, it was reported that Black Seed oil has an anti-inflammatory effect and that it could be useful for relieving arthritis pain. Following up on these claims, a group of scientists from Kings College, Department of Pharmacy, London, decided to test Black Seed oil and its derivative thymoquinone as an anti-inflammatory agent. It was discovered that the agents possessed anti-oxidant activity and inhibited eicosanoid generation in cells. Certain eicosanoids (short lived local tissue hormones) are responsible for the inflammatory response whereas anti-oxidants help to slow cartilage degeneration.



The inhibitory effect on eicosanoid generation, however, was higher than could be expected from thymoquinone alone. This suggests that other compounds in the oil might be responsible for the enhanced anti-inflammatory reactions in cells. Researchers concluded that pharmacological properties of Black Seed and its derived products support the traditional use of Black Seed as a treatment for rheumatism and related inflammatory diseases.



In Europe ongoing scientific research has fueled immense public interest into the health benefits of using Black Seed, particularly in Austria and Germany, where Black Seed supplements are sold in most health stores and it is popularly regarded as an effective alternative medicine. It also has been the subject of intensive scientific research indicating that it strengthens and stabilizes the immune system and is greatly beneficial in the treatment of allergies. It has been found to be beneficial in the treatment of impotence when the causes are primarily physiological.



It seems Black Seed can be helpful for just about anything. However its use is not recommended during pregnancy. While much still remains to be investigated, studies conducted thus far, confirm Black Seed as a natural panacea.



Suggestions for using Black Seed

Black Seed is available as pure oil and capsules. Either form may be taken preventively and for immune support. For arthritis, swallow capsules; apply pure oil to affected area.



For respiratory problems, dilute oil (1 part Black Seed oil to 5 parts olive oil), rub on chest and back; heat some oil and inhale the vapors. For head cold, rub forehead and sides of face close to the ears with Black Seed oil.



As an energy tonic, take the oil in orange juice in the morning. In spite of it being used for energy, Black Seed also relieves insomnia. For sleep disturbances, take one teaspoon of Black Seed oil and one teaspoon of honey in warm milk. Rub the temp-les with the oil and turn of the lights.



Whole seeds can be found in many Indian and Persian markets and can be used in baked goods and pickles. Crush the seeds to use in beverages, curries or as a pepper substitute.



Until recently not many people knew of Ginseng. Now, the name is practically a household word. Will Americans discover Black Seed and accept it as an invaluable health tonic? Historical records and modern scientific research cannot be discounted.









--------------------------------------------------------------------------------



TESTIMONIALS



After taking the gel tabs for only a few weeks, I noticed several changes.

After taking the gel tabs for only a few weeks, I noticed several changes. My cholesterol that had been high was now under control. I put away my prescription for a well known allergy medication. And so far... flu season has passed me by.





Martha A.

Plantation

Black Seed Effects on the Immune System

Black Seed Effects on the Immune System


Black Seed could play an important role in the treatment of cancer, AIDS, and other immune deficiency states.



Several studies point to the effect of black seed and thymoquinone on the immune system by modulating the levels of pro- and anti-inflammatory mediators. Thymoquinone has also been shown to inhibit inflammation and oxidative stress in cells. The seeds have been shown to produce an increase in the ratio of helper to suppressor T cells and enhance natural killer cell activity in healthy volunteers. Because thymoquinone has dual anti-oxidant and anti-inflammatory activities, it may be an instrument which not only prevents the direct harmful effects of oxidants, but it may essentially alter the underlying inflammatory processes that play an important role in the pathogenesis of inflammatory bowel disease and colorectal cancer.



In the field of AIDS research, human clinical trials conducted at the Department of Biological and Medical Research Center in Riyadh, Saudi Arabia showed that Black Seed enhanced the ratio between helper T-cell by 55% with a 30% enhancement of NK cell activity. These findings suggest that Black Seed could play an important role in the treatment of cancer, AIDS, and other immune deficiency states.






Badary OA, Taha RA, Gamal el-Din AM, et al. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol. 2003 May;26(2):87-98.



El-Kadi A, Kandil O, Tabuni AM, Nigella sativa and cell mediated immunity. Arch AIDS Res. 1989; 1: 232–233.



Gali-Muhtasib H, Roessner A, Schneider-Stock R. Thymoquinone: a promising anti-cancer drug from natural sources. Int J Biochem Cell Biol. 2006;38(8):1249-53.



Hajhashemi V, Ghannadi A, Jafarabadi H. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytother Res. 2004 Mar;18(3):195-9.



Haq A, Lobo PI, Al-Tufail M, et al. Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography. Int J Immunopharmacol. 1999 Apr;21(4):283-95.



Haq A, Abdullatif M, Lobo PI, et al. Nigella sativa: effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity. Immunopharmacology. 1995 Aug;30(2):147-55.



Houghton PJ, Zarka R, de las Heras B, et al. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 1995 Feb;61(1):33-6.



Mansour MA, Nagi MN, El-Khatib AS, et al. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Cell Biochem Funct. 2002 Jun;20(2):143-51.




TESTIMONIALS



I started taking the capsules this year during the cold and flu season to help my immune system.

I started taking the capsules this year during the cold and flu season to help my immune system. For several weeks my co-workers were getting sick one after another, but I felt healthier than usual. I was amazed at how much stronger I felt! Eventually I did catch the cough/cold that had been going around (stress and extended lack of sleep will do that to you, no matter how strong your immunity). However, I got better at least 5 times faster than my co-workers with the same illness -- I only had to take 1 sick day. With a high-stress job, this is a supplement I don't want to go without. The other benefits (clearing skin, improving hair) are a nice bonus, too!



Amina

Alexandria, Virginia

Diabetes Prevention by using Black Seed

Diabetes Prevention by using Black Seed


Diabetes mellitus results in severe metabolic imbalances and pathological changes in many tissues. Oxidative stress has been shown to play an important role in the etiology of diabetes and diabetic complications. Diabetics exhibit high-oxidative stress due to persistent and chronic hyperglycemia, thereby reducing the activity of the antioxidative defense system and thus promoting free radical generation.



Several interactive pathogenetic mechanisms of diabetic peripheral neuropathy have been identified in both human and murine models and persistent hyperglycaemia has been regarded as a primary risk factor for neuropathy. Long-term hyperglycaemia can lead to subsequent enhanced oxidative stress, increased aldose reductase activity, and accumulation of advanced glycation endproducts (AGE). As a result, it could induce progressive damage to the peripheral sensory and autonomic nervous systems. To date, except for rigorous glycaemic control, there are few means to affect or slow the natural progression of diabetic peripheral neuropathy owing to limitations of the current and often inadequate drug therapy.



However, in a recent animal study, scientists found Nigella sativa and its pharmacologically active substance thymoquinone, affected blood glucose levels, and insulin. Furthermore, they suggested that the antioxidant activity of black seed may alleviate damage to b-cells in the pancreas. The study found less damage to tissues in diabetic animals treated with black seed and thymoquinone. The researchers concluded that the neuroprotective effects of thymoquinone and especially black seed are attributed to its direct and indirect antioxidant actions.




Babaei-Jadidi R, Karachalias N, Ahmed N, et al. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes. 2003 Aug;52(8):2110-20.



Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes. 1991 Apr;40(4):405-12.



Cameron NE, Cotter MA, Basso M, et al. Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats. Diabetologia. 1997 Mar;40(3):271-81.



Kanter M. Effects of Nigella sativa and its major constituent, thymoquinone on sciatic nerves in experimental diabetic neuropathy. Neurochem Res. 2008 Jan;33(1):87-96.



Karachalias N, Babaei-Jadidi R, Ahmed N, et al. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochem Soc Trans. 2003 Dec;31(Pt 6):1423-5.



Le PM, Benhaddou-Andaloussi A, Elimadi A, et al. The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat. J Ethnopharmacol. 2004 Oct;94(2-3):251-9.



[No authors listed] The effect of intensive diabetes therapy on the development and progression of neuropathy. The Diabetes Control and Complications Trial Research Group. Ann Intern Med. 1995 Apr 15;122(8):561-8.



[No authors listed] Failure of improved glycaemic control to reverse diabetic autonomic neuropathy. The St Thomas's Diabetic Study Group. Diabet Med. 1986 Jul-Aug;3(4):330-4.



Thorpe SR, Baynes JW. Role of the Maillard reaction in diabetes mellitus and diseases of aging. Drugs Aging. 1996 Aug;9(2):69-77.



Vague P, Coste TC, Jannot MF, et al. C-peptide, Na+,K(+)-ATPase, and diabetes. Exp Diabesity Res. 2004 Jan-Mar;5(1):37-50.






TESTIMONIALS



After taking the gel tabs for only a few weeks, I noticed several changes.

After taking the gel tabs for only a few weeks, I noticed several changes. My cholesterol that had been high was now under control. I put away my prescription for a well known allergy medication. And so far... flu season has passed me by.

Black Seed Cardiovascular Benefits

Black Seed Cardiovascular Benefits


Black seed can be used as an antihypertensive agent.



It has been suggested that black seed oil could be effectively used to treat hypertension. This lends credibility to the folkloric use of the oil as an antihypertensive agent. The methanol soluble portion of the oil showed inhibitory effects on arachidonic acid induced platelet aggregation and blood coagulation. What's more, several compounds displayed anticoagulation effects more potent than aspirin, which is a common therapeutic agent for thrombosis. A French study found that the dichloromethane extract of black seed shows strong diuretic and antihypertensive actions. In fact, the authors suggested that the diuretic action of black seed might be, at least partially, responsible for its antihypertensive action related to its volatile oils.



Another study reported that the oral treatment of rats with black seed oil decreased serum cholesterol, triglyceride and glucose levels, and leucocyte and platelet counts by about 15–35%, compared to control values. These results indicate a possible beneficial effect of the oil in hyperglycaemia and hyperlipidema, and probably as an adjunct to the treatment of certain types of anaemia. Several extracts of Nigella sativa significantly reduced plasma triglycerides while increasing HDL-cholesterol. Besides, one study reported that the volatile oil of Nigella sativa was as efficient as the cholesterol-reducing drug simvastatin. As a matter of fact, a study involving nine students found that two capsules of 500 mg of black seed oil twice daily for two weeks was able to reduce blood levels of both glucose and cholesterol.



Moreover, scientific evidence also indicates that black seed oil and thymoquinone are effective in reducing homocysteine levels. Evidence using animal models suggests that homocysteine causes direct oxidant injury to the vasculature, impairs the vasodilator and anticoagulation function of nitrous oxide, stimulates smooth muscle proliferation, interferes with clotting factors and increases oxidative stress. Black seed oil may offer an alternative for homcysteine reduction to those people that do not respond to folic acid, vitamins B12 and or B6.









--------------------------------------------------------------------------------



Bamosa AO, Ali BA, Sowayan SA. Effect of oral ingestion of Nigella sativa seeds on some blood parameters. Saudi Pharm J. 1997;5:126–129.



el Tahir KE, Ashour MM, al-Harbi MM. The cardiovascular actions of the volatile oil of the black seed (Nigella sativa)in rats: elucidation of the mechanism of action. Gen Pharmacol. 1993 Sep;24(5):1123-31.



Enomoto S, Asano R, Iwahori Y, et al. Hematological studies on black cumin oil from the seeds of Nigella sativa L. Biol Pharm Bull. 2001 Mar;24(3):307-10.



Labhal A, Settaf A, Bennani N, et al. Action anti-obésité et hypocholestérolémiante de Nigella sativa chez le rat des sables. 1997 Caducée 27:26–28.



Le PM, Benhaddou-Andaloussi A, Elimadi A, et al. The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat. J Ethnopharmacol. 2004 Oct;94(2-3):251-9.



Settaf A, Berrada Y, Haddad PS, et al. Volatile oil of Nigella sativa lowers plasma lipids and insulin in obese hyperlipidemic sand rats (Psammomys obesus). 2000 6th International Congress on Ethnopharmacology:P2A/36.



Stamler JS, Slivka A. Biological chemistry of thiols in the vasculature and in vascular-related disease. Nutr Rev. 1996 Jan;54(1 Pt 1):1-30.



Tsai JC, Perrella MA, Yoshizumi M, et al. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6369-73.



van Guldener C, Stehouwer CD. Hyperhomocysteinemia, vascular pathology, and endothelial dysfunction. Semin Thromb Hemost. 2000;26(3):281-9.



Zaoui A, Cherrah Y, Mahassini N, et al. Acute and chronic toxicity of Nigella sativa fixed oil. Phytomedicine. 2002 Jan;9(1):69-74.



Zaoui A, Cherrah Y, Lacaille-Dubois MA, et al. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat] [Article in French] Therapie. 2000 May-Jun;55(3):379-82.


TESTIMONIALS



I have suffered from allergies all my life

"I have suffered from allergies all my life. I took a small sample from a friend during a bad attack. The next morning I rushed to buy my own supply. It really worked a miracle in me within 24 hours.

Brunnie T.

Fort Lauderdale, FL

Cancer Prevention by using Black Seed

Cancer Prevention by using Black Seed


Very recently, researchers at Kimmel Cancer at Jefferson in Philadelphia discovered that thymoquinone blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death. Using a human pancreatic cancer cell line, researchers found that adding thymoquinone killed approximately 80 percent of the cancer cells. They showed that thymoquinone triggered programmed cell death in the cells, and that a number of important genes, including p53, Bax, bcl-2 and p21, were affected. Expression of p53, a tumour suppressor gene, and Bax, a gene that promotes programmed cell death, was increased, while bcl-2, which blocks such cell death, was decreased. The p21 gene, which is involved in the regulation of different phases of the cell cycle, was substantially increased. Researchers also found that thymoquinone caused epigenetic changes in pancreatic cancer cells, modifying the cells DNA.



In a recent animal study, thymoquinone treatment not only inhibited tumor cell invasion and proliferation in C26 colorectal cancer cells but, also reduced the growth of colon cancer cells in two different in vivo models. Tumor growth inhibition by thymoquinone is believed to be attributed to its potent antiinflammatory and antioxidant effects, in addition to the induction of apoptosis. Oxygen radicals, especially nitric oxide, cause p53 gene mutations, chromosomal change and activation of signal transduction pathways involved in cell growth. Thymoquinone has been shown to inhibit superoxide anions and nitric oxide production involved in tumorigenesis.



Many investigators have shown that the growth inhibitory effects of thymoquinone are specific to cancer cells. In fact, thymoquinone has shown significant anti-neoplastic activity against human pancreatic adenocarcinoma, uterine sarcoma and leukemic cell lines, while it is only minimally toxic to normal cells.



What's more, thymoquinone treatment has been found to alleviate the toxicity of several anticancer drugs by reducing their toxicity to the heart, kidney, liver and central nervous system.









--------------------------------------------------------------------------------



al-Shabanah OA, Badary OA, Nagi MN, et al. Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity. J Exp Clin Cancer Res. 1998 Jun;17(2):193-8.



Arafat H. 18 May at the Digestive Disease Week in San Diego.



Badary OA, Taha RA, Gamal el-Din AM, et al. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol. 2003 May;26(2):87-98.



Badary OA, Nagi MN, al-Shabanah OA, et al. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol. 1997 Dec;75(12):1356-61.



Cerutti PA. Oxy-radicals and cancer. Lancet. 1994 Sep 24;344(8926):862-3.



El-Mahmoudy A, Shimizu Y, Shiina T, et al. Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism. Int Immunopharmacol. 2005 Jan;5(1):195-207.



El-Mahmoudy A, Matsuyama H, Borgan MA, et al. Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages. Int Immunopharmacol. 2002 Oct;2(11):1603-11.



Gali-Muhtasib H, Ocker M, Kuester D, et al. Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models. J Cell Mol Med. 2008 Jan-Feb;12(1):330-42.



Gali-Muhtasib H, Roessner A, Schneider-Stock R. Thymoquinone: a promising anti-cancer drug from natural sources. Int J Biochem Cell Biol. 2006;38(8):1249-53.



Gali-Muhtasib HU, Abou Kheir WG, Kheir LA, et al. Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes. Anticancer Drugs. 2004 Apr;15(4):389-99.



Mansour MA, Nagi MN, El-Khatib AS, et al. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Cell Biochem Funct. 2002 Jun;20(2):143-51.



Mansour MA, Ginawi OT, El-Hadiyah T, et al. Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone. Res Commun Mol Pathol Pharmacol. 2001;110(3-4):239-51.



Mansour MA. Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice. Life Sci. 2000 May 19;66(26):2583-91.



Salomi NJ, Nair SC, Jayawardhanan KK, et al. Antitumour principles from Nigella sativa seeds. Cancer Lett. 1992 Mar 31;63(1):41-6.



Worthen DR, Ghosheh OA, Crooks PA. The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L. Anticancer Res. 1998 May-Jun;18(3A):1527-32.









--------------------------------------------------------------------------------



TESTIMONIALS



Worked really great for overall health. More energy too.

Worked really great for overall health. More energy too. I have a shoulder injury from sports and it took away the pain as it is also has anti-inflammatory properties.



Sometimes I had to use over the counter pain killers, but immediately stopped using it after reading an article titled: The Dangers of Aspirin & NSAIDS



What should I know about Non-Steroidal Anti-Inflammatory Drugs (NSAIDS)



The second major cause for ulcers is irritation of the stomach arising from regular use of non-steroidal anti-inflammatory drugs, or NSAIDs. NSAIDs are available over-the-counter (OTC) and by prescription.



If you are taking over-the-counter pain medications on a regular basis, you will want to talk with your physician about the potential for ulcers and other GI side effects. NSAID-induced gastrointestinal side effects can be reduced by using alternative therapy. Your doctor may recommend that you change the medication you are using; or add some other medication in conjunction with your pain medication.



You can see the article here:

http://www.acg.gi.org/patients/women/asprin.asp

Black Seed Helps in Combatting Asthma

Black Seed Helps in Combatting Asthma


Negative environmental factors can cause an increase in allergic diseases. Childhood mortality due to bronchial asthma has more than doubled during the past decade. In the United States, approximately 200 children die of asthma each year; over 150,000 are hospitalized because of asthma, and around 5 million have the disease. Bronchial asthma is a genetically based, multifactorial disease that is aggravated by a number of factors such as infections, allergen exposure, tobacco smoke and environmental pollutants. Likewise, hay fever, a typical inhalation allergy, is generally triggered by wind-borne pollen and represents the acute form of seasonal allergic rhinitis.



The lymphatic system of the intestines and bronchi is constantly confronted with numerous food and environmental antigens. In addition to its defensive function, the lymphatic system must ensure tolerance to its own intestinal flora and other substances. Stabilization of the arachidonic acid metabolism via modulation of prostaglandin and leukotriene production, and stabilization of interleukins and tumour necrosis factor (TNF) has been shown to safeguard the body from allergic reactions.



Scientific evidence indicates that black seed oil contains pharmacologically active substances such as thymoquinones, dithymoquinones, thymohydroquinones and thymol that modify leukotriene synthesis and inhibit histamine release. Some of the studies that evaluated the antiallergic potency of black seed oil in animals demonstrated that even small concentrations of its active constituents effectively inhibited the release of histamine from mast cells.



Four human studies showed that black seed oil is indeed capable of relieving symptoms of allergic rhinitis, atopic eczema, and bronchial asthma. The effect of black seed oil on inhalation allergies, the most common type of allergic disease, was determined in two placebo-controlled studies (one in children and one in adults) and in two open-label studies also involving children and adults. Depending on their body weight, the patients took three to seven 500 mg of Egyptian black seed oil capsules each day. Improvement of allergy symptoms was observed in all four studies. The complaints of patients with allergic rhinitis decreased significantly. This was especially evident in the studies involving children, where approximately 80% of the children had improvement of allergic rhinitis symptoms. The children with bronchial asthma treated in the open-label studies study also had relevant and significant improvement of clinical symptoms. Nigella sativa oil also proved to be very effective in adult subjects with allergic rhinitis.



A possible explanation for the positive clinical effects observed in the human studies can be drawn from animal experiments. One study for example, showed that Nigella sativa oil inhibited the cyclooxygenase and 5- lipoxygenase pathways of arachidonic acid metabolism, resulting in the decreased synthesis of thromboxane and leukotrienes. Leukotrienes, in particular, are contributing factors for the development of bronchial asthma since they develop proinflammatory activity. Leukotriene receptor antagonists are therefore used for treatment of bronchial asthma. Researchers have not only found that this effect is induced by thymoquinone, but other compounds of black seed oil as well.



In Arabian folk medicine, black seed alone or in combination with honey is used as a treatment for bronchial asthma. In a recent study involving twenty-nine asthmatic adults, black seed given for three months, significantly improved all asthma symptoms including chest wheezing and pulmonary functions tests. Furthermore, the usage of inhalers and other asthma medications decreased in the patients receiving black seed. The researchers believed the results of the study confirmed previous studies indicating a relaxant effect of black seed on airway smooth muscle. They also noted the antitussive effect of black seed oil.









--------------------------------------------------------------------------------





Boskabady MH, Javan H, Sajady M, et al. The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients. Fundam Clin Pharmacol. 2007 Oct;21(5):559-66.



Boskabady MH, Kiani S, Jandaghi P, et al. Antitussive of Nigella sativa. Pak J Med Sci. 2004; 20: 224-228.



Boskabady MH, Shahabi M. Bronchodilatory and anticholinergic effects of Nigella sativa on isolated guinea-pig tracheal chains. Iran J Med Sci. 1997; 22: 127-133.



Chakravarty N. Inhibition of histamine release from mast cells by nigellone. Ann Allergy. 1993

Mar;70(3):237-42.



Ghosheh OA, Houdi AA, Crooks PA. High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). J Pharm Biomed Anal. 1999 Apr;19(5):757-62.



Houghton PJ, Zarka R, de las Heras B, et al. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 1995 Feb;61(1):33-6.



Jäger L, Kroegel C. [Leukotriene receptor antagonists and bronchial asthma] [Article in German] Arzneimittelforschung. 1998 Mar;48(3):205-11.



Kalus U, Pruss A, Bystron J, et al. Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases. Phytother Res. 2003 Dec;17(10):1209-14.



Landrigan PJ, Carlson JE, Bearer CF, et al. Children's health and the environment: a new agenda for prevention research. Environ Health Perspect. 1998 Jun;106 Suppl 3:787-94.








TESTIMONIALS



I have suffered from allergies all my life

"I have suffered from allergies all my life. I took a small sample from a friend during a bad attack. The next morning I rushed to buy my own supply. It really worked a miracle in me within 24 hours.

Brunnie T.

Black seed is effective against Gram-positive than Gram-negative organisms

Black seed is effective against Gram-positive than Gram-negative organisms


Antimicrobial

A number of reports have been published on the actions of black seed extracts or its oil on different strains of bacteria. The extract and the oil have been reported to have a broad spectrum of activity against a number of microbes. For example, in vitro antibacterial effects of the essential oil showed pronounced activity even in minute dilutions against several organisms that included Staphylococcus albus, Escherichia coli, Salmonella typhi, Shigella niger and Vibrio cholera. Generally speaking the oil was more effective against Gram-positive than Gram-negative organisms.



The oil was also found to have excellent antifungal activity, particularly against Aspergillus species. Another study confirmed the effectiveness of Nigella sativa against Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The antibacterial effect was maximal when Bacillus subtilis was used. It has been shown that both the crude alkaloid extract and the water extract of the seeds were effective against a variety of organisms (isolated from human patients suffering from septic arthritis), even those that were resistant to antibiotics. Finally, black seed oil, given intraperitoneally, has been shown to exhibit a potent action against murine cytomegalovirus infection in mice.



The action was suggested to be related to the potentiating action of the oil on innate immunity. Scientific data has suggested the potential of Nigella sativa as a natural source for the production of new antifungal drugs.

References

Agarwal R, Kharya MD, Shrivastava R. Antimicrobial & anthelmintic activities of the essential oil of Nigella sativa Linn. Indian J Exp Biol. 1979 Nov;17(11):1264-5.



Aljabre SH, Randhawa MA, Akhtar N, et al. Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone. J Ethnopharmacol. 2005 Oct 3;101(1-3):116-9.



El-Kamali HH, Ahmed AH, Mohammed AS, et al. Antibacterial properties of essential oils from Nigella sativa seeds, Cymbopogon citatus leaves and Pulicaria undulata aerial parts. Fitoterapia 1998; 34:77–78.



Morsi NM. Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria. Acta Microbiol Pol. 2000;49(1):63-74.



Salem ML, Hossain MS. Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. Int J Immunopharmacol. 2000 Sep;22(9):729-40.



Toppozada HH, Mazloum HA, el-Dakhakhny M. The antibacterial properties of the Nigella sativa l. seeds. Active principle with some clinical applications. J Egypt Med Assoc. 1965;48:Suppl:187-202.









--------------------------------------------------------------------------------



TESTIMONIALS



I have had bronchitis for as long as I can remember.

I have had bronchitis for as long as I can remember. Every year, it got worst until finally the Doctors told me I had adult onset asthma. I tried the gel tabs about 4 days ago. I could hardly believe that within hours of the first dose, I was able to take nice deep breaths. I'm looking forward to swimming and jogging again when the weather warms up.





Marcy H.

Tallahassee, FL

Black Seed Usage as an Anti-Inflammatory Substance

Black Seed Usage as an Anti-Inflammatory Substance


Animal studies have confirmed the popular claim that black seed is an effective antiinflammatory and analgesic substance. The mechanism by which black seed exerts its antiinflammatory action appears to be as a potent inhibitor of eicosanoid generation, namely thromboxane B2 and leucotrienes B4, by inhibiting both cyclooxygenase and lipooxygenase, respectively. In other studies, thymoquinone has been reported to have potent superoxide anion scavenging abilities and to inhibit iron-dependent microsomal lipid peroxidation.



This is promising considering the fact that superoxide reacts with protein and non-protein sulfhydryls and polyunsaturated fats and initiates sprecific reactions, thus damaging cells and causing inflammation. Meanwhile free radical oxidative stress is implicated in many inflammatory diseases. Therefore, it is reasonable that the anti-inflammatory activities of thymoquinone are attributed to its antioxidant effects. Interestingly, it was found that the whole oil had both antioxidant and anti-eicosanoid effects greater than thymoquinone, the oil's active constituent.



A recent study found black seed and thymoquinone may be an effective treatment for rheumatoid arthritis. This comes as no surprise, since it has been shown that thymoquinone is an inhibitor that is more potent than indomethacin of COX-2-catalyzed PGE2 production.



The immuno-modulatory properties of black seed and thymoquinone support its traditional use as a treatment for rheumatism and related inflammatory disorders.

References

Abdel-Fattah AM, Matsumoto K, Watanabe H. Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice. Eur J Pharmacol. 2000 Jul 14;400(1):89-97.



Al-Ghamdi MS. The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa. J Ethnopharmacol. 2001 Jun;76(1):45-8.



Badary OA, Taha RA, Gamal el-Din AM, et al. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol. 2003 May;26(2):87-98.



Gali-Muhtasib H, Roessner A, Schneider-Stock R. Thymoquinone: a promising anti-cancer drug from natural sources. Int J Biochem Cell Biol. 2006;38(8):1249-53.



Ghannadi A, Hajhashemi V, Jafarabadi H. An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. J Med Food. 2005 Winter;8(4):488-93.



Hajhashemi V, Ghannadi A, Jafarabadi H. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytother Res. 2004 Mar;18(3):195-9.



Houghton PJ, Zarka R, de las Heras B, et al. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 1995 Feb;61(1):33-6.



Marsik P, Kokoska L, Landa P, et al. In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1- and -2-catalyzed prostaglandin E2 biosyntheses. Planta Med. 2005 Aug;71(8):739-42.



Mutabagani A, El-Mahdi SM. A study of the anti-inflammatory activity of Nigella sativa L. and thymoquinone in rats. 1997 Saudi Pharmacol J. 5: 110–113


TESTIMONIALS



I have suffered from cat virus in 2009 and made me bedriddened for more than 3 months.

"I have suffered from cat virus in 2009 and made me bedriddened for more than 3 months. I went to Government Hospitals and 2 Private Clinic to get medication but could not cure my illness. I searched from the internet all sorts of health food and tried them but my illness worsened. At last I found out Nigella Sativa (Black Seed) and tried consuming it. After taking about 12 bottles of the product I was cured entirely. Thanks to my brother Mr Mahmoud Ayesh who supported me all the way long. I suggest everybody consume this wonderful product for protection for the whole family.



Izhar Haroon

Selangor, Malaysia

Black Seed Helps in Combating Allergies

Black Seed Helps in Combating Allergies


Negative environmental factors can cause an increase in allergic diseases. Childhood mortality due to bronchial asthma has more than doubled during the past decade. In the United States, approximately 200 children die of asthma each year; over 150,000 are hospitalized because of asthma, and around 5 million have the disease. Bronchial asthma is a genetically based, multifactorial disease that is aggravated by a number of factors such as infections, allergen exposure, tobacco smoke and environmental pollutants. Likewise, hay fever, a typical inhalation allergy, is generally triggered by wind-borne pollen and represents the acute form of seasonal allergic rhinitis.



The lymphatic system of the intestines and bronchi is constantly confronted with numerous food and environmental antigens. In addition to its defensive function, the lymphatic system must ensure tolerance to its own intestinal flora and other substances. Stabilization of the arachidonic acid metabolism via modulation of prostaglandin and leukotriene production, and stabilization of interleukins and tumour necrosis factor (TNF) has been shown to safeguard the body from allergic reactions.



Scientific evidence indicates that black seed oil contains pharmacologically active substances such as thymoquinones, dithymoquinones, thymohydroquinones and thymol that modify leukotriene synthesis and inhibit histamine release. Some of the studies that evaluated the antiallergic potency of black seed oil in animals demonstrated that even small concentrations of its active constituents effectively inhibited the release of histamine from mast cells.



Four human studies showed that black seed oil is indeed capable of relieving symptoms of allergic rhinitis, atopic eczema, and bronchial asthma. The effect of black seed oil on inhalation allergies, the most common type of allergic disease, was determined in two placebo-controlled studies (one in children and one in adults) and in two open-label studies also involving children and adults. Depending on their body weight, the patients took three to seven 500 mg of Egyptian black seed oil capsules each day. Improvement of allergy symptoms was observed in all four studies. The complaints of patients with allergic rhinitis decreased significantly. This was especially evident in the studies involving children, where approximately 80% of the children had improvement of allergic rhinitis symptoms. The children with bronchial asthma treated in the open-label studies study also had relevant and significant improvement of clinical symptoms. Nigella sativa oil also proved to be very effective in adult subjects with allergic rhinitis.



A possible explanation for the positive clinical effects observed in the human studies can be drawn from animal experiments. One study for example, showed that Nigella sativa oil inhibited the cyclooxygenase and 5- lipoxygenase pathways of arachidonic acid metabolism, resulting in the decreased synthesis of thromboxane and leukotrienes. Leukotrienes, in particular, are contributing factors for the development of bronchial asthma since they develop proinflammatory activity. Leukotriene receptor antagonists are therefore used for treatment of bronchial asthma. Researchers have not only found that this effect is induced by thymoquinone, but other compounds of black seed oil as well.



In Arabian folk medicine, black seed alone or in combination with honey is used as a treatment for bronchial asthma. In a recent study involving twenty-nine asthmatic adults, black seed given for three months, significantly improved all asthma symptoms including chest wheezing and pulmonary functions tests. Furthermore, the usage of inhalers and other asthma medications decreased in the patients receiving black seed. The researchers believed the results of the study confirmed previous studies indicating a relaxant effect of black seed on airway smooth muscle. They also noted the antitussive effect of black seed oil.

Black Seed and Acne

Black Seed and Acne


Studies have shown that black seed oil contains antioxidants that protect the body from free radicals. Additionally black seed oil is a tremendous source of essential fatty acids. Adding this natural remedy to your daily routine is an excellent way to maintain great health.



By keeping your body free of irritants and fats that are not very healthy for you to consume you can limit if not end completely any potential acne breakouts that you might experience.



THE APPLICATION OF BLACK SEED OIL TREATMENT

When taking black seed oil it is recommended that you take one to two soft gels daily. Preferably, you should take this natural remedy around the same time that you eat or at a time that has been recommended by your health care provider.



If you suffer from any type of arthritis or joint problems be aware that black seed oil may possibly cause arthritic flare ups if too much is taken. If you have any concerns at all about adding a supplement of any kind to your diet make sure to check with your health care provider. You doctor will be able to give you the most informed opinion on if it would have adverse effects on you should you take it.



If you have tried product after product and no over the counter acne remedy is helping your skin clear up then you need to give black seed oil a try. Over a period of time with safe and consistent use black seed oil can aide in clearing up your acne problems and will have you feeling great on the inside as well.









--------------------------------------------------------------------------------



TESTIMONIALS



I used to have to monitor my blood sugar daily.

I used to have to monitor my blood sugar daily. I added the Black Seed Oil to my diet and now my body regulates my sugar levels. Thank God. No more medication.





Mr Hypolite

Kingston, Jamaica

Kalonji Seeds

Kalonji Seeds
Kalonji seeds are the small black granules found in the fruits of Nigella sativa plant which is an annual herbaceous plant which belongs to the Ranunculaceae family. This is native plant of south west Asia that is abundantly cultivated in India, Bangladesh, Turkey and other Eastern countries.



The plant has erect stem, light green finely divided leaves, blue and white star shaped flowers and fruits bearing black seeds. These are usually triangular, tiny and hairy seeds of no more than 3mm in length and possess a severe pungent smell.



Chemical Composition



The chemical composition of black seed is very rich and diverse. Aside from its primary ingredient, crystalline nigellone, this Nigella Sativa Seed contains 15 amino acids, proteins, carbohydrates, essential fatty acids, 1.5% volatile oils, 37.5% non volatile oils, alkaloids, saponin, crude fiber and other minerals. However all the components of Black Seed haven't been identified till now. But research is going on around the world.









Biochemical Constituents



The Kalonji seeds mainly constitute of alanine, arginine, ascorbic-acid, asparagine, campesterol, carvone, cymene, cystine, dehydroascorbic-acid, eicosadienoic-acid, glucose, glutamic-acid, glycine, iron, isoleucine, leucine,linolenic-acid, lipase, lysine, methionine, myristic-acid, nigellin, nigellone, oleic-acid, palmitic-acid, phenylalanine, phytosterols, potassium, beta-sitosterol, alpha-spinasterol, stearic-acid, stigmasterol, tannin, threonine, thymohydroquinone, thymoquinone, tryptophan, tyrosine, limonene and linoleic-acid.









Nutritional Components of Kalonji/Black Seeds



Kalonji Seed or Black Seed contains more than hundred valuable nutrients. It contains about 21% Protein, 38% carbohydrates and 35% plant fats and oils. The contents are similar to evening primrose oil, but because of its complex composition, it is much stronger.



The active ingredients of black seed are Thymoquinone, Nigellone and Fixed oils. It also contains in significant proportions proteins, carbohydrates, and essential fatty acids. Other ingredients include Linoleic acid, Oleic acid, Calcium, Potassium, Iron, Zinc, Magnesium, Selenium, Vitamin A, Vitamin B, Vitamin B2, Niacin and Vitamin C.





Nutritional Value of Kalonji / Black Seed



Kalonji/Black seeds are rich in nutritional values.

Black Seed contains Monosaccharides in the form of glucose, rhamnose, xylose, and arabinose.

A non-starch polysaccharide component which is a useful source of dietary fiber is found in black seed.

Fifteen amino acids make up the protein content of the black seed. It is rich in unsaturated and essential fatty acids which cannot be manufactured by the body alone.

Black seed contains arginine which is essential for infant growth.

They contain carotene, which is converted by the liver into vitamin A, the vitamin known for its anti-cancer activity.

As these possess minerals like calcium, iron, sodium and potassium, they have anti-bacterial properties, anti-tumor principles, show anti-histamine activity and help to promote lactation.



The average nutritional values of Black Seeds are as follows:



Nutrient Average Contents of black cumin Per 100 g on wet Basis USRDA6 %ofUS INQ%

Energy (kcal (MJ) 531(222) 2300(9,63) 23.1 1.0

Protein (g) 20.8 65 32 1.4

Thiamin (mg) 1.5 1.5 100 4.3

Riboflavin (mg) 0.1 1.7 509 0.3

Pyridoxine (mg) 0.5 2 25 1.1

Niacin (mg) 5.7 20 28.5 1.2

Calcium (mg) 185.9 1000 18.6 0.8

Iron (mg) 10.5 18 58.3 2.5

Copper (mg) 1.8 2 90 3.9

Zinc(mg) 6 15 40 1.7

Phosphorus (mg) 526.5 1000 52.7 2.3

Folacin (mg) 0.061 0.4 15.3 0.7

Index of nutritional quality (INQ) Per



(Gutherie1989)





Analysis of Volatile Oil in Black Seed



Black seeds contain considerable amounts of essential oil. The analysis of the volatile oil (essential oil) content in the black seed reveals chemical compounds that have been proven to exert all of these actions. The seed, which contains 1 of 4 of volatile oils has the following composition:



Volatile Oil Percent (%) Properties

Cymene 32 % Known to have been used for its local analgesic actions, in rheumatic conditions.

Pinene 3 % When taken internally has mild expectorant and colic properties and when used externally has similar actions to Cymene.

Carbony 25 % Responsible for the antiseptic and anti-microbial properties of the seed. Extensive microbiological tests have confirmed its action against gram-positive as well as gram-negative organisms.

Carvone 0.05 % Known for its anti-colic and flatulence properties.

Limonene 27 % Reported to be effective in the treatment of gallstones.

Nigellon

semohiprepinon 1.5 % When inhaled or rubbed on the chest, it enlarges the bronchi, dissolves cramps and raises their temperature which quickly alleviates symptoms due to bronchial asthma and whooping cough. Also inhibits the release of histamine.

Thymochinon Inhibits infection, relieves pain, stimulates the gall bladder and works as an anti oxidant.





Properties



Black seeds have properties of stimulant, aromatic, carminative, digestive, diuretic, emmenagogue, excitant, galactatagogue, purgative, resolvent, stomachic, sudorific, tonic, and vermifuge.



The recent discoveries and researches reveal that the black seeds are superior to almost every other natural remedy when used for autoimmune disorders, especially when combined with garlic, it acts as a harmonizer of the imbalance which allows immune cells to destroy healthy cells.



The Black Seed has been used for variety of conditions and for treatment related to respiratory health, stomach, intestinal and heart complaints, kidney & lever function, circulatory & immune system support. Nearly 70% of all traditional ayurvedic formulas contain black seed as important ingredient.

Kalonji seeds are most effective in treating diabetes, cancer, asthma, dry cough, paralysis, polio, toothache, headache, earache, obesity, jaundice, hair problems, eye diseases, heart complaints, skin problems, uterus problems, ladies diseases, and various other health ailments all over the world.



Therefore it is not at all wrong to mention these as “The Blessed Seeds”.

Kalonji Oil Application

Kalonji Oil Application


Therapeutic Applications:

Prophet Muhammad once stated that the black seed has the cure for every illness except death. The protective and healing powers of Kalonji seeds and Kalonji Oil are so astoundingly comprehensive and varied that for thousands of years humans have regarded it as a "Miracle Cure".

Black Seed Oil contains more than 100 components, some of which are still unidentified, that work together synergistically. It is a rich source of polyunsaturated fatty acids or essential fatty acids which are the building blocks of cells and help the body produce Prostaglandin E1. It is an excellent healer and its areas of application range from external skin care (psoriasis, eczema, dry skin, joints & scalp massage) to internal use as a treatment for various complaints (asthma, arthritis, immune system).

Black seeds are rich sources of calcium, iron, sodium and potassium. Required in small amounts of body, these elements help to strengthen immune system, promote lactation and thus give the oil therapeutic uses as anti-histamine, anti-pyretic, anti-inflammatory, antioxidant, anti-tumor and anti-bacterial.

Modern research indicates use of Kalonji oil as analgesic that dampens sensation of pain, anthelmintic that destroys intestinal worms, anti-bacterial that inhibits the growth of bacteria, anti-spasmodic that eases muscle cramps, anti-tumor that prevents the formation of tumors, carminative that stimulates digestion, diaphoretic that induces perspiration during fever to cool, diuretic stimulating urination to relieve bloating, galactogogue for stimulating the action of milk in new mothers, immunomodulator that strengthens immune system activity as needed for optimum balance and laxative which causes relaxation of the bowels.

KALONJI OIL WHEN TAKEN AS APPROPRIATE DOSAGE CAN BE MOST EFFECTIVE IN TREATING NUMBER OF HEALTH AILMENTS LIKE:

HYPERTENSION DIABETES COUGH & ASTHMA

HEART ATTACK CANCER LADIES DIESEASES

SKIN DIESEASES HEADACHE & EARACHE BACKACHE

HAIR PROBLEMS TOOTHACHE GASTROINTESTINAL

DENTAL DISEASES

HYPERTENSION:
Hypertension or High Blood Pressure is also called as “The silent Killer “because it can develop several potentially fatal complications such as heart attacks or strokes. Black Seed Oil or Kalonji Oil offers the best cure for this disease as it stimulates the production of Prostoglandin E1 in the body that helps to lower blood pressure. It releases excess fluid and thus helps to relieve arterial pressure.

Recommended dosage:

Take half teaspoon of Black seed oil with any hot drink at any time.

Take 2 lobes of garlic daily on empty stomach.

DIABETES:

Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels, that result from defects in insulin secretion.

There are two types of diabetes.

Type 1 diabetes

Type 2 diabetes.
Type 1 diabetes is usually diagnosed in children and young adults as body does not produce insulin where as



Type 2 diabetes is caused body does not produce enough insulin or the cells ignore the insulin.



Obesity or overweight is the main cause of Type II Diabetes. Benefits of Black seed oil for diabetes in human beings have been confirmed by well known physician and herbalist Muhammed Salim Khan. Black seed oil with good diet has revealed to reduce blood glucose levels significantly.
Recommended Dosage:
Mix half tea spoon of Kalonji oil in hot water and drink it twice daily once in the morning and also before going to bed.

Avoid oily food stuff, particularly fried items.

COUGH & ASTHMA:

Asthma is a chronic lung disease that inflames and narrows the airways. Asthma causes recurring periods of wheezing, chest tightness, shortness of breath, and coughing. Kalonji oil offers excellent treatment for cough and asthma when taken according to this dosage.
Recommended Dosage:
Mix teaspoon of Kalonji oil in boiling water and inhale the vapour twice a day. Take half teaspoon of Kalonji oil daily in the morning.
Apply Kalonji oil to chest and back


HEART ATTACK, SWELLING ON BREATHING VEINS:
Kalonji Oil is proven to be effective treatment for ailments like blockage of heart valve, breathing problem, cold sweating and pressure on heart. A heart attack occurs when blood flow to a section of heart muscle becomes blocked. This occurs mainly when the triglycerides levels in cholesterol increase. These fatty particles travel through the blood and have the potential to stick to the vessel walls causing occlusions resulting in a heart stroke. Kalonji oil helps to reduce the levels of triglycerides in cholesterol thus reducing chances of heart attack.
Recommended Dosage:

Take half tea spoon of Kalonji oil mixed with any hot drink daily in the morning.

This will liquefy the fats and open the veins and arteries. Avoid fatty items.

CANCER:
Black seed has been identified to be highly beneficial in the treatment of cancer as it contains components like thymoquinoline and dithymoquinone that have been shown to inhibit tumour cells. Patented by the FDA in USA in 2 separate cases for the treatment of cancer, black seed oil is considered serious remedy for cancer which can prevent the side effects of anti cancer chemo-therapy and support the immune system.

Recommended Dosage:

Take one glass grape juice and half tea spoon Kalonji oil and use thrice a day once in the morning before breakfast, after lunch and after dinner.

Take one kg barley and two kgs of wheat flour, mix together, make bread (roti) and give to the patient for forty days.

Avoid Potato, Arvee and Brinjal.


LADIES DIESEASES:
Kalonji oil is proven to be most effective in curing the most common diseases that most of the women across the globe suffer from. These ladies diseases are stoppage of menses for long term, stomach pain and other secret diseases like Leucorrhoea, White Discharge, Menses discharges 2 to 4 times a month, stomach pain and back pain.

Recommended Dosage:
In case of ladies diseases like Leucorrhoea, white discharge, menses discharges 2 to 4 times a month, stomach pain and back pain dosage is -

Take two glasses of water and put 25 gms of mint, boil for 20 minutes. Add half tea spoon Kalonji oil. Drink before the breakfast and after dinner for forty days. Avoid pickles, brinjal egg and fish.

For stoppage of menses for long term, stomach pain the dosage is -
Take one cup of warm water add half tea spoon kalonji oil and two spoons honey one time in the morning before the breakfast and in the night after dinner. Treatment may continue for month. Avoid potato and Brinjal.

SKIN DIESEASES, PIMPLES, BOILS, PSORIASIS:

Black seed oil may be used to heal a number of skin conditions. Since black seed oil alleviates itching and aids in preventing infection, it's an effective way to treat psoriasis without the use of prescription drugs.

Recommended Dosage:
For psoriasis, mix juice of six limes with 50 gms of Kalonji oil and rub on the affected areas.

For skin diseases, pimples and boils before going to bed apply Kalonji oil on the affected areas of the body, in the morning wash with soap. Continue this treatment for 21 days.
HEADACHE & EARACHE:
Black seed oil is proven very effective for treating headaches by regulating the hormonal system, promoting prostaglandin effect and increasing elimination of uric acid. It is the best remedy for relief from earaches.

Recommended Dosage:

Apply Black Seed oil to the forehead, the sides of face adjacent to the ears and behind the ears.

Take half teaspoon of Kalonji oil for 3 days.


BACKACHE AND RHEUMATIC PAINS

Rheumatism refers to the medical problems of joints and connective tissues. Rheumatics often suffer from intestinal mycosis and the formation of too many acid toxins. For backache and rheumatism, black seed oil is the best solution. It has an anti-inflammatory effect that reduces crystallisation and improves blood circulation in the painful areas of the body.

Recommended Dosage:
Warm Kalonji oil slightly & apply to the area thoroughly, massaging the bone, not the skin & drink half teaspoon of Kalonji oil for 30 days.
HAIR PROBLEMS, HAIR LOSS:
Black seed strengthens the scalp and hair follicles and reduces hair fall. Massaging the hair with Black Seed Oil regularly may prevent premature hair graying.
Scrub the scalp thoroughly with lemon juice, leave it for 15 minutes & shampoo & let dry then apply Kalonji oil to whole scalp, continue for 6 weeks.

TOOTHACHE:
Black Seed Oil has been found to be very effective at treating toothaches. To alleviate the soreness and pain, simply rub a small amount of the oil on the affected gum and tooth, and repeat for 15 seconds.
You can also mix a half teaspoon of Black Seed Oil in a small glass of warm water, and gargle with it.

GASTROINTESTINAL PROBLEMS:

Black Seed oil contains saponin, melanthin and nigellin, having strong eliminating qualities cleaning the intestines and also increasing urine secretion therefore releasing more toxins. It is thus most effective in treating ailments like flatulence, heartburn, constipation and intestinal fungi.

DENTAL DISEASES:
For dental problems like premature fall of teeth, weakness of teeth, flow of blood from the teeth, bad smell of the mouth, swelling on gums take one cup of curd and half tea spoon of Kalonji oil, use this mixture twice a day, once in the morning before the breakfast and at night after dinner.
Not only for these Kalonji oil can also be used for treating jaundice, eye diseases, piles, stomach problems like digestive problems, constipation, dyspepsia & worms in stomach, dysentery, anemia, epilepsy, uterus problems, arthritis, polio, leprosy, nausea, vomiting, meningitis, obesity, chest irritations and weaknesses in men.

Applications in Food Preparation:

Black seed oil is a rich source of nutritional value and contains monosaccharides and non-starch polysaccharide component which is useful source of dietary fibre. It contains essential fatty acids which cannot be prepared by body alone therefore we acquire them through food.
In food main application area of Nigella lies in Turkey, Libanon and Iran especially in bread preparation. From Iran, Nigella has stepped into Northern India where it is used for vegetable dishes. It is fried or dry-roasted before usage to enhance the taste. In the states of West Bengal and Sikkim it is used in the preparation of panch phoron, a spicy mixture used to flavor meat dishes.



DISCLAIMER: Please note that these dosages are taken from traditional and modern applications. In the case of illness one should always contact a physician to be absolutely sure. The statements made here have not been evaluated by the FDA, and as such, shall not be construed as medical advice, implied or otherwise.

Where to buy Black seed oil


http://www.theblessedseed.com/


http://www.regenerativenutrition.com/


http://www.taylor-jackson.com//